The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China.
Department of Gynecology, First Affiliated Hospital of Xi 'an Medical College, Xi'an 710000, China.
Int J Biol Macromol. 2023 Jul 1;242(Pt 4):125192. doi: 10.1016/j.ijbiomac.2023.125192. Epub 2023 Jun 3.
Hydrogels is a hydrophilic, cross-linked polymer of three-dimensional network structures. The application of hydrogels prepared from a single polymer in the biomedical field has many drawbacks. The functional blend of polyvinyl alcohol and chitosan allows hydrogels to have better and more desirable properties than those produced from a single polymer, which is a good biomaterial for development and design. In this paper, we have reviewed the progress in the application of polyvinyl alcohol/chitosan composite hydrogels in various medical fields, the different cross-linking agents and cross-linking methods, and the research progress in the optimization of composite hydrogels for their subsequent wide range of biomedical applications.
水凝胶是一种具有亲水性的三维网络结构的交联聚合物。由单一聚合物制备的水凝胶在生物医学领域的应用有许多缺点。聚乙烯醇和壳聚糖的功能共混使水凝胶具有比由单一聚合物制备的水凝胶更好和更理想的性能，是一种用于开发和设计的良好生物材料。本文综述了聚乙烯醇/壳聚糖复合水凝胶在各个医学领域的应用进展、不同的交联剂和交联方法以及对复合水凝胶进行优化以用于随后的广泛生物医学应用的研究进展。
