Ophthalmology Unit, Department of Inmunology, Ophthalmology and ORL, Faculty of Medicine, Hospital Clinico San-Carlos, Universidad Complutense de Madrid and Instituto de Investigación Sanitaria del Hospital Clínico San-Carlos (IdISSC), Calle del Prof Martín Lagos, s/n, 28040, Madrid, Spain.
Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain.
Int Ophthalmol. 2023 Oct;43(10):3491-3497. doi: 10.1007/s10792-023-02754-7. Epub 2023 Jun 7.
To compare intraocular pressure (IOP) measurements obtained using the new transpalpebral Easyton® tonometer and Perkins applanation tonometer (PAT) in three different clinical populations.
The participants of this prospective study were 84 subjects divided into the groups: 22 healthy children (G1), 42 healthy adults (G2), and 20 adult patients with primary open angle glaucoma (G3). The data recorded in 84 eyes of these subjects were age, sex, gender, central corneal thickness (CCT), and axial length (AL). In all eyes, IOP was determined in the same examination room by the same experienced examiner using Easyton® and PAT in random order.
Mean differences in IOP readings between Easyton® and PAT were 0.45 ± 1.97 (p = 0.295), - 0.15 ± 2.13 (p = 0.654), - 1.65 ± 3.22 (p = 0.033), and - 0.018 ± 2.50 mmHg (p = 0.500) in the groups G1, G2, G3, and whole sample (G4), respectively. Correlations between Easyton® and PAT IOP values were 0.668 (p = 0.001) for G1, 0.463 (p = 0.002) for G2, 0.680 (p < 0.001) for G3, and 0.605 (p < 0.001) for G4. Moderate to good agreement between the two tonometers was found in all groups according to intraclass correlation coefficients, which were 0.794 (p < 0.001) for G1, 0.632 (p < 0.001) for G2, 0.809 (p < 0.001) for G3, and 0.740 (p < 0.001) for G4. The lower and upper limits of agreement between the devices were - 5.1 and 4.7 mmHg, respectively, in the complete group. No correlation was noted between CCT or AL and the Easyton® IOP measurements.
IOP measurements obtained with Easyton® and PAT show an acceptable level of agreement mainly in healthy individuals, recommending it for IOP screening in children and in patients in which PAT measurement may be impared as patients with hemifacial spasms, corneal irregularities, or reduced mobility. It is not recommended for glaucoma patients follow-up.
比较新型经皮易通(Easyton®)眼压计和 Perkins 压平眼压计(PAT)在三种不同临床人群中的眼压(IOP)测量值。
本前瞻性研究的参与者为 84 名受试者,分为三组:22 名健康儿童(G1)、42 名健康成年人(G2)和 20 名原发性开角型青光眼成年患者(G3)。这些受试者的 84 只眼中记录的数据有年龄、性别、性别、中央角膜厚度(CCT)和眼轴(AL)。所有受试者均在同一检查室内由同一位经验丰富的检查者以随机顺序使用易通(Easyton®)和帕坦(PAT)进行 IOP 测量。
易通(Easyton®)和帕坦(PAT)的 IOP 读数差值在 G1 组、G2 组、G3 组和整个样本(G4)中分别为 0.45±1.97(p=0.295)、-0.15±2.13(p=0.654)、-1.65±3.22(p=0.033)和-0.018±2.50mmHg(p=0.500)。G1 组、G2 组、G3 组和 G4 组的易通(Easyton®)和帕坦(PAT)IOP 值之间的相关性分别为 0.668(p=0.001)、0.463(p=0.002)、0.680(p<0.001)和 0.605(p<0.001)。根据组内相关系数,两组眼压计在所有组中均显示出中度至良好的一致性,G1 组为 0.794(p<0.001)、G2 组为 0.632(p<0.001)、G3 组为 0.809(p<0.001)、G4 组为 0.740(p<0.001)。两种仪器的下限和上限差值分别为-5.1mmHg 和 4.7mmHg,适用于整个组。在易通(Easyton®)眼压测量值中未发现 CCT 或 AL 有相关性。
易通(Easyton®)和帕坦(PAT)的眼压测量值具有可接受的一致性水平,主要适用于健康人群,推荐用于儿童的眼压筛查,以及在帕坦(PAT)测量可能受损的情况下,如面肌痉挛、角膜不规则或运动受限的患者。不建议青光眼患者随访时使用。