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尿失禁作为早期韦尼克脑病的主要临床表现:一例报告

Urinary incontinence as a main clinical manifestation of early stage Wernicke's encephalopathy: a case report.

作者信息

He Haitian, Wang Kebing, Wang Yang, Luo Jinbin

机构信息

Department of Urology, Shenzhen Qianhai Shekou Free Trade Zone Hospital, Shenzhen, China.

Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.

出版信息

Front Neurol. 2023 May 24;14:1157806. doi: 10.3389/fneur.2023.1157806. eCollection 2023.

DOI:10.3389/fneur.2023.1157806
PMID:37292136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10246772/
Abstract

Wernicke's encephalopathy (WE) is a condition caused by a deficiency of vitamin B1. While there have been many reported cases of WE in the literature, there are few reports on the early stages of the disorder. In this report, we present a case of WE with urinary incontinence as the main clinical manifestation. A 62-year-old female patient was admitted to the hospital due to intestinal obstruction and did not receive vitamin B1 supplements for 10 days. Three days after her operation, she developed urinary incontinence. She also had mild mental symptoms, such as a little indifference. After consultation with a urologist and neurologist, the patient was immediately given intramuscular vitamin B1 at a dosage of 200 mg/day. After 3 days of supplementing with vitamin B1, her urinary incontinence and mental symptoms improved and were completely resolved after 7 days of treatment. Surgeons should be aware that when long-term fasting patients have urinary incontinence, it may be a symptom of WE, and they should be supplied with vitamin B1 in a timely manner without extensive examination.

摘要

韦尼克脑病(WE)是一种由维生素B1缺乏引起的疾病。虽然文献中有许多关于WE的报道病例,但关于该疾病早期阶段的报道却很少。在本报告中,我们呈现了一例以尿失禁为主要临床表现的WE病例。一名62岁女性患者因肠梗阻入院,10天未补充维生素B1。术后三天,她出现了尿失禁。她还伴有轻度精神症状,如稍有淡漠。在咨询泌尿科医生和神经科医生后,立即给予该患者每日200毫克的肌肉注射维生素B1。补充维生素B1三天后,她的尿失禁和精神症状有所改善,治疗7天后完全缓解。外科医生应意识到,长期禁食患者出现尿失禁时,可能是WE的症状,应及时补充维生素B1,无需进行广泛检查。

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本文引用的文献

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Urinary dysfunction after colorectal cancer treatment and its impact on quality of life - a national cross-sectional study in women.结直肠癌治疗后尿功能障碍及其对生活质量的影响-一项全国范围内女性的横断面研究。
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Biomarkers of delirium as a clue to diagnosis and pathogenesis of Wernicke-Korsakoff syndrome.谵妄的生物标志物可作为韦尼克-科尔萨科夫综合征的诊断和发病机制线索。
Eur J Neurol. 2013 Dec;20(12):1531-8. doi: 10.1111/ene.12217. Epub 2013 Jun 21.
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Urinary incontinence after surgery for pelvic organ prolapse.盆腔器官脱垂手术后的尿失禁。
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9
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