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早产儿和婴儿的血小板生成活性。

Thrombopoietic activity in preterm newborns and infants.

作者信息

Sirota L, Bessler H, Weissman Z, Dulitzky F, Djaldetti M

出版信息

Arch Dis Child. 1986 Jun;61(6):585-8. doi: 10.1136/adc.61.6.585.

Abstract

Platelet count and thrombopoietic activity were investigated in preterm infants at birth and during their first four months of life. Thrombopoiesis stimulating factor activity in cord serum was significantly lower than that of adults and of the respective mothers. No difference was noted between thrombopoietic activity in cord serum in the various gestational ages studied--that is, 24 through 39 weeks. Preterm infants followed during their first four months of life showed a mean platelet count significantly higher than that observed in term infants at the respective age. Furthermore, thrombocytosis was found in premature thriving infants at the age of 1 and 2 months. It is suggested that this thrombocytosis is responsible for the low thrombopoietic activity observed in these infants during their first four months of life.

摘要

对早产儿出生时及出生后头四个月的血小板计数和血小板生成活性进行了研究。脐血血清中血小板生成刺激因子活性显著低于成人及各自母亲。在所研究的不同胎龄(即24至39周)的脐血血清中,血小板生成活性未发现差异。在出生后头四个月进行跟踪研究的早产儿,其平均血小板计数显著高于同龄足月儿。此外,在1个月和2个月大的生长良好的早产儿中发现了血小板增多症。有人认为,这种血小板增多症是导致这些婴儿出生后头四个月血小板生成活性较低的原因。

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Thrombopoietic activity in newborn infants.新生儿的血小板生成活性。
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IL-1 beta and IL-3-like activity in preterm infants.早产儿中的白细胞介素-1β和白细胞介素-3样活性
Clin Exp Immunol. 1993 Feb;91(2):320-4. doi: 10.1111/j.1365-2249.1993.tb05902.x.

本文引用的文献

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Isotope bioassay for "thrombopoietin".“血小板生成素”的同位素生物测定法。
Br Med J. 1970 Mar 7;1(5696):606-8. doi: 10.1136/bmj.1.5696.606.
9
Thrombocytosis in infants and children.婴幼儿血小板增多症。
J Pediatr. 1974 Dec;85(6):805-7. doi: 10.1016/s0022-3476(74)80345-8.
10
Thrombopoietic activity in newborn infants.新生儿的血小板生成活性。
Biol Neonate. 1986;49(2):61-5. doi: 10.1159/000242511.

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