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早产儿和婴儿的血小板生成活性。

Thrombopoietic activity in preterm newborns and infants.

作者信息

Sirota L, Bessler H, Weissman Z, Dulitzky F, Djaldetti M

出版信息

Arch Dis Child. 1986 Jun;61(6):585-8. doi: 10.1136/adc.61.6.585.

DOI:10.1136/adc.61.6.585
PMID:3729528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1777849/
Abstract

Platelet count and thrombopoietic activity were investigated in preterm infants at birth and during their first four months of life. Thrombopoiesis stimulating factor activity in cord serum was significantly lower than that of adults and of the respective mothers. No difference was noted between thrombopoietic activity in cord serum in the various gestational ages studied--that is, 24 through 39 weeks. Preterm infants followed during their first four months of life showed a mean platelet count significantly higher than that observed in term infants at the respective age. Furthermore, thrombocytosis was found in premature thriving infants at the age of 1 and 2 months. It is suggested that this thrombocytosis is responsible for the low thrombopoietic activity observed in these infants during their first four months of life.

摘要

对早产儿出生时及出生后头四个月的血小板计数和血小板生成活性进行了研究。脐血血清中血小板生成刺激因子活性显著低于成人及各自母亲。在所研究的不同胎龄(即24至39周)的脐血血清中,血小板生成活性未发现差异。在出生后头四个月进行跟踪研究的早产儿,其平均血小板计数显著高于同龄足月儿。此外,在1个月和2个月大的生长良好的早产儿中发现了血小板增多症。有人认为,这种血小板增多症是导致这些婴儿出生后头四个月血小板生成活性较低的原因。

相似文献

1
Thrombopoietic activity in preterm newborns and infants.早产儿和婴儿的血小板生成活性。
Arch Dis Child. 1986 Jun;61(6):585-8. doi: 10.1136/adc.61.6.585.
2
Thrombopoietic activity in newborn infants.新生儿的血小板生成活性。
Biol Neonate. 1986;49(2):61-5. doi: 10.1159/000242511.
3
Early elevation of serum thrombopoietin levels and subsequent thrombocytosis in healthy preterm infants.健康早产儿血清血小板生成素水平早期升高及随后的血小板增多症
Br J Haematol. 2001 Dec;115(4):963-8. doi: 10.1046/j.1365-2141.2001.03183.x.
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Thrombocytosis in preterm infants: a possible involvement of thrombopoietin receptor gene expression.早产儿血小板增多症:血小板生成素受体基因表达的可能参与
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The thrombopoietin level in the cord blood in premature infants born to mothers with pregnancy-induced hypertension.妊娠高血压综合征母亲所生早产儿脐带血中血小板生成素水平
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Humoral regulation of erythropoiesis and thrombopoiesis in appropriate and small for gestational age infants.适于胎龄儿和小于胎龄儿红细胞生成和血小板生成的体液调节
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Mean platelet volume and platelet distribution width in the neonate.新生儿的平均血小板体积和血小板分布宽度
Am J Pediatr Hematol Oncol. 1987 Summer;9(2):130-2. doi: 10.1097/00043426-198722000-00002.

引用本文的文献

1
IL-1 beta and IL-3-like activity in preterm infants.早产儿中的白细胞介素-1β和白细胞介素-3样活性
Clin Exp Immunol. 1993 Feb;91(2):320-4. doi: 10.1111/j.1365-2249.1993.tb05902.x.

本文引用的文献

1
Differentiation of murine marrow megakaryocyte progenitors (CFUm): humoral control in vitro.小鼠骨髓巨核细胞祖细胞(CFUm)的分化:体外体液控制
Cell Tissue Kinet. 1981 Jan;14(1):53-8. doi: 10.1111/j.1365-2184.1981.tb00510.x.
2
Plasma thrombopoietic activity in humans with normal and abnormal platelet counts.血小板计数正常和异常的人类血浆中的血小板生成活性。
Blood. 1980 Aug;56(2):183-8.
3
Humoral regulation of erythropoiesis and thrombopoiesis in appropriate and small for gestational age infants.适于胎龄儿和小于胎龄儿红细胞生成和血小板生成的体液调节
Acta Paediatr Scand. 1982 Sep;71(5):769-73. doi: 10.1111/j.1651-2227.1982.tb09517.x.
4
Assay of an activity in the serum of patients with disorders of thrombopoiesis that stimulates formation of megakaryocytic colonies.对血小板生成障碍患者血清中一种刺激巨核细胞集落形成的活性物质的检测。
N Engl J Med. 1981 Sep 3;305(10):533-8. doi: 10.1056/NEJM198109033051001.
5
Megakaryocyte maturation rate in thrombocytopenic rats.血小板减少症大鼠的巨核细胞成熟率
Blood. 1968 Nov;32(5):787-95.
6
Platelet counts in thriving premature infants.发育良好的早产儿的血小板计数
Pediatrics. 1968 Oct;42(4):685-9.
7
Isotope bioassay for "thrombopoietin".“血小板生成素”的同位素生物测定法。
Br Med J. 1970 Mar 7;1(5696):606-8. doi: 10.1136/bmj.1.5696.606.
8
Bioassay for thrombopoietin utilizing mice in rebound thrombocytosis.利用小鼠反弹性血小板增多症进行血小板生成素的生物测定。
Proc Soc Exp Biol Med. 1973 Dec;144(3):1006-12. doi: 10.3181/00379727-144-37730.
9
Thrombocytosis in infants and children.婴幼儿血小板增多症。
J Pediatr. 1974 Dec;85(6):805-7. doi: 10.1016/s0022-3476(74)80345-8.
10
Thrombopoietic activity in newborn infants.新生儿的血小板生成活性。
Biol Neonate. 1986;49(2):61-5. doi: 10.1159/000242511.