Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Int J Mol Sci. 2023 May 31;24(11):9600. doi: 10.3390/ijms24119600.
Rapid, accurate, and convenient diagnosis is essential for effective disease management. Various detection methods, such as enzyme-linked immunosorbent assay, have been extensively used, with lateral flow immunoassay (LFIA) recently emerging as a major diagnostic tool. Nanoparticles (NPs) with characteristic optical properties are used as probes for LFIA, and researchers have presented various types of optical NPs with modified optical properties. Herein, we review the literature on LFIA with optical NPs for the detection of specific targets in the context of diagnostics.
快速、准确、便捷的诊断对于有效的疾病管理至关重要。各种检测方法，如酶联免疫吸附测定法，已经得到广泛应用，而侧向流动免疫分析（LFIA）最近也成为一种主要的诊断工具。具有特征光学性质的纳米粒子（NPs）被用作 LFIA 的探针，研究人员已经提出了各种具有改良光学性质的光学 NPs。在此，我们综述了有关 LFIA 与光学 NPs 用于诊断背景下特定靶标检测的文献。
