School of Mathematical and Physical Sciences, Faculty of Science, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Molecules. 2023 May 28;28(11):4396. doi: 10.3390/molecules28114396.
is native to Western Australia. It has become an introduced and fast-growing plant in other parts of the world due to its ability to adapt to drought, saline and alkaline soils, and hast growing environments. Studies on the bioactivities and phytochemicals of the plant extracts were conducted. However, comprehensive information that links those bioactivities to the identified compounds in the plant's extracts is still lacking. Data gathered in this review revealed a rich chemical diversity of hydroxybenzoic acids, cinnamic acids, flavonoids, saponins, and pinitols in growing in Egypt, Saudi Arabia, Tunisia, South Africa, and Australia. The variability in phytochemical composition and quantity could be attributed to plant parts, growing locations, extraction solvents, and analysis methods. Identified phytochemicals support observed biological activities such as antioxidant, antimicrobial, anticancer, α-glucosidase inhibition, and anti-inflammation in the extracts. The knowledge of chemical structures, biological activities, and possible mechanisms of action of the bioactive phytochemicals identified in were discussed. In addition, the structure-activity relationships of dominant active compounds were examined to explain the bioactivities exerted by extracts. The review provides valuable insights towards future research and the development of new therapeutics from this plant.
原产于澳大利亚西部。由于其适应干旱、盐碱和碱性土壤以及快速生长环境的能力,它已成为世界其他地区的引入和快速生长的植物。对植物提取物的生物活性和植物化学物质进行了研究。然而,将这些生物活性与植物提取物中鉴定的化合物联系起来的综合信息仍然缺乏。本综述中收集的数据揭示了在埃及、沙特阿拉伯、突尼斯、南非和澳大利亚生长的 中存在丰富的化学多样性,包括羟基苯甲酸、肉桂酸、类黄酮、皂苷和松醇。植物化学组成和数量的可变性可能归因于植物部位、生长地点、提取溶剂和分析方法。鉴定的植物化学物质支持观察到的生物活性,如抗氧化、抗菌、抗癌、α-葡萄糖苷酶抑制和抗炎作用在提取物中。讨论了从 中鉴定出的生物活性植物化学物质的化学结构、生物活性和可能的作用机制。此外,还检查了主要活性化合物的结构-活性关系,以解释 提取物发挥的生物活性。该综述为未来的研究和从该植物开发新的治疗方法提供了有价值的见解。