Lalonde R, Botez M I, Boivin D
Behav Neurosci. 1986 Jun;100(3):350-2. doi: 10.1037//0735-7044.100.3.350.
Nervous mutant mice have a selective degeneration of Purkinje cells and deep cerebellar nuclei. In comparison with littermate controls, nervous mutant mice did not alternate spontaneously in a successive trial procedure (six consecutive trials per day) and did not habituate in a restricted part of a t-maze in a 4-min session. These data indicate that the cerebellum may have a role in spatial learning.
神经突变小鼠的浦肯野细胞和小脑深部核团会发生选择性退化。与同窝对照小鼠相比,神经突变小鼠在连续试验程序(每天连续进行六次试验)中不会自发交替,并且在4分钟的t迷宫受限区域内也不会产生习惯化。这些数据表明小脑可能在空间学习中发挥作用。