Prevalence and Phylogenetic Analysis of and Virulent Factor among Ulcerative Colitis Precancerous and Colorectal Carcinoma Patients in the Iraqi Kurdish Population.

is considered one of the main risk factors that play a key role in the promotion and progression of colorectal carcinoma. The main goal of this study is to find out the association between the prevalence of various subtypes of with inflammation and colorectal cancer progression, in addition to screening the positive ratio of the possession of the gene. One hundred tissue samples were collected from healthy individuals and patients from colonoscopy and surgical operation biopsies. The patients were categorized into (Ulcerative colitis, precancerous colitis and colorectal carcinoma) according to their colonoscopy and histopathology examination reports. Molecular detection of and gene was performed via PCR and gel electrophoresis, and then phylogenetic analysis for was done using 16S rRNA partial sequencing based on specific primers. The results showed significant differences among the four groups regarding the prevalence of . The most prevalent subtype was subtype animalis, which constitutes 7 out of 17 samples. The ratio of the -positive gene was 20% among the -positive cases. This finding suggested a strong correlation between and colon inflammation and cancer progression steps, and subtype animalis was the most prevalent subtype.