Robertson A S, Weir D C, Burge P S
Occupational Lung Disease Unit, East Birmingham Hospital.
Thorax. 1988 Mar;43(3):200-5. doi: 10.1136/thx.43.3.200.
Twenty five patients who were exposed to oil mists at their place of work were investigated for possible work related asthma. Serial peak expiratory flow recordings showed 13 to have definite work related asthma, seven equivocal work related asthma, and three asthma unrelated to work; two had normal recordings. Subjects with work related asthma often produced different patterns of peak flow response during the working week; patterns also varied between patients. Six of these patients had bronchial tests with oil from their place of work. Three had asthma induced by exposure to unused (clean) soluble oil and one reacted to used but not to clean oil. The challenge tests in the remaining two gave inconclusive results. It is concluded that occupational asthma due to oil mists is common, the peak flow response is heterogeneous, and the provoking agent within the oil may vary from worker to worker.
对25名在工作场所接触油雾的患者进行了调查，以确定是否可能患有与工作相关的哮喘。连续的呼气峰值流速记录显示，13名患者患有明确的与工作相关的哮喘，7名患者可能患有与工作相关的哮喘，3名患者的哮喘与工作无关；2名患者的记录正常。患有与工作相关哮喘的受试者在工作周期间通常会产生不同的峰值流速反应模式；不同患者之间的模式也有所不同。其中6名患者用工作场所的油进行了支气管测试。3名患者因接触未使用过的（清洁的）可溶性油而诱发哮喘，1名患者对用过的油有反应，但对清洁油无反应。其余2名患者的激发试验结果不明确。得出的结论是，油雾引起的职业性哮喘很常见，峰值流速反应具有异质性，而且油中的诱发因素可能因工人而异。
