文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

Recent applications of immunomodulatory biomaterials for disease immunotherapy.

作者信息

Dai Huaxing, Fan Qin, Wang Chao

机构信息

Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Soochow University 199 Ren'ai Road Suzhou Jiangsu China.

Key Laboratory for Organic Electronics & Information Displays (KLOEID) Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials (IAM) and School of Materials Science and Engineering Nanjing University of Posts & Telecommunications Nanjing China.

出版信息

Exploration (Beijing). 2022 May 23;2(6):20210157. doi: 10.1002/EXP.20210157. eCollection 2022 Dec.

DOI:10.1002/EXP.20210157
PMID:37324799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10191059/
Abstract

Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat various diseases. Biomaterial-based immunotherapy systems can improve therapeutic effects through targeted drug delivery, immunoengineering, etc. However, the immunomodulatory effects of biomaterials themselves cannot be neglected. In this review, we outline biomaterials with immunomodulatory functions discovered in recent years and their applications in disease treatment. These biomaterials can treat inflammation, tumors, or autoimmune diseases by regulating immune cell function, exerting enzyme-like activity, neutralizing cytokines, etc. The prospects and challenges of biomaterial-based modulation of immunotherapy are also discussed.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/1d8c36028b0b/EXP2-2-20210157-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/19e0086ccc2e/EXP2-2-20210157-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/7793b510209e/EXP2-2-20210157-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/b7b879dbdae8/EXP2-2-20210157-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/7a77f1170a13/EXP2-2-20210157-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/a949ffd087d4/EXP2-2-20210157-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/48918ef5db81/EXP2-2-20210157-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/26a597209aa0/EXP2-2-20210157-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/1d8c36028b0b/EXP2-2-20210157-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/19e0086ccc2e/EXP2-2-20210157-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/7793b510209e/EXP2-2-20210157-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/b7b879dbdae8/EXP2-2-20210157-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/7a77f1170a13/EXP2-2-20210157-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/a949ffd087d4/EXP2-2-20210157-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/48918ef5db81/EXP2-2-20210157-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/26a597209aa0/EXP2-2-20210157-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b9e/10191059/1d8c36028b0b/EXP2-2-20210157-g002.jpg

相似文献

[1]
Recent applications of immunomodulatory biomaterials for disease immunotherapy.

Exploration (Beijing). 2022-5-23

[2]
Immunoengineering the next generation of arthritis therapies.

Acta Biomater. 2021-10-1

[3]
Tailoring Materials for Modulation of Macrophage Fate.

Adv Mater. 2021-3

[4]
Advances in immunotherapy delivery from implantable and injectable biomaterials.

Acta Biomater. 2019-2-13

[5]
Immunoengineering with biomaterials for enhanced cancer immunotherapy.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018-1-14

[6]
Biomaterials as Local Niches for Immunomodulation.

Acc Chem Res. 2020-9-15

[7]
Implantable and Injectable Biomaterial Scaffolds for Cancer Immunotherapy.

Front Bioeng Biotechnol. 2020-11-30

[8]
Oral drug delivery for immunoengineering.

Bioeng Transl Med. 2021-8-10

[9]
Supramolecular Biomaterials for Cancer Immunotherapy.

Research (Wash D C). 2023-9-12

[10]
Mechanical Immunoengineering of T cells for Therapeutic Applications.

Acc Chem Res. 2020-12-15

引用本文的文献

[1]
Responsive biomaterials for therapeutic strategies of hepatocellular carcinoma.

Front Bioeng Biotechnol. 2025-8-20

[2]
Mitochondrial Metabolism in T-Cell Exhaustion.

Int J Mol Sci. 2025-7-31

[3]
Dual Roles of SIRT7 Inhibition by Oroxylin A Reprogram HSCs Fate: PRMT5 Succinylation-Driven Senescence and Ecto-Calreticulin-Dependent NK Cell Immune Clearance in Liver Fibrosis.

Research (Wash D C). 2025-8-7

[4]
Tertiary Amine Oxide-Containing Zwitterionic Polymers: From Material Design to Biomedical Applications.

Pharmaceutics. 2025-6-27

[5]
Biomaterials mediated 3R (remove-remodel-repair) strategy: holistic management of Helicobacter pylori infection.

J Nanobiotechnology. 2025-7-1

[6]
Design Principles Of Inorganic-Protein Hybrid Materials for Biomedicine.

Exploration (Beijing). 2025-3-6

[7]
Organic AIE Nanoradiosensitizer Potentiates X-Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy.

Adv Mater. 2025-9

[8]
Optimizing delivery in a multivalent subunit influenza vaccine using mixed polymeric microparticle degradation rates.

J Control Release. 2025-8-10

[9]
Nanozyme-driven multifunctional dressings: moving beyond enzyme-like catalysis in chronic wound treatment.

Mil Med Res. 2025-5-31

[10]
Near-infrared smart responsive orthopedic implants with synergistic antimicrobial and bone integration-promoting properties.

J Orthop Translat. 2025-4-9

本文引用的文献

[1]
Degradation-resistant implanted biomaterials establish an immunosuppressive microenvironment that induces T cell exhaustion by recruiting myeloid cells.

Fundam Res. 2021-11-25

[2]
Yeast-derived nanoparticles remodel the immunosuppressive microenvironment in tumor and tumor-draining lymph nodes to suppress tumor growth.

Nat Commun. 2022-1-10

[3]
A Minimalist Binary Vaccine Carrier for Personalized Postoperative Cancer Vaccine Therapy.

Adv Mater. 2022-3

[4]
Inorganic Nanozymes: Prospects for Disease Treatments and Detection Applications.

Front Chem. 2021-11-25

[5]
Nanozymes in Tumor Theranostics.

Front Oncol. 2021-10-19

[6]
Ferumoxytol Nanoparticles Target Biofilms Causing Tooth Decay in the Human Mouth.

Nano Lett. 2021-11-24

[7]
Engineered Cell Membrane-Derived Nanoparticles in Immune Modulation.

Adv Sci (Weinh). 2021-12

[8]
Inhaled ACE2-engineered microfluidic microsphere for intratracheal neutralization of COVID-19 and calming of the cytokine storm.

Matter. 2022-1-5

[9]
Carbon-Based Nanomaterials Increase Reactivity of Primary Monocytes towards Various Bacteria and Modulate Their Differentiation into Macrophages.

Nanomaterials (Basel). 2021-9-27

[10]
MSC-Derived Extracellular Vesicles in Tumors and Therapy.

Cancers (Basel). 2021-10-18

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索