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基于天然生物分子的抗菌水凝胶用于快速伤口愈合:综述。

Natural biomarocmolecule-based antimicrobial hydrogel for rapid wound healing: A review.

机构信息

Department of Solid Mechanics, Faculty of Mechanical Engineering, University of Kashan, P.O. Box 87317-53153, Kashan, Iran.

Department of Microbiology, Faculty of Biological Science, Alzahra University, Tehran, Iran.

出版信息

Int J Biol Macromol. 2023 Jul 31;244:125454. doi: 10.1016/j.ijbiomac.2023.125454. Epub 2023 Jun 16.

DOI:10.1016/j.ijbiomac.2023.125454
PMID:37331533
Abstract

Antibacterial hydrogels are a type of hydrogel that is designed to inhibit the growth of bacteria and prevent infections. These hydrogels typically contain antibacterial agents that are either integrated into the polymer network or coated onto the surface of the hydrogel. The antibacterial agents in these hydrogels can work through a variety of mechanisms, such as disrupting bacterial cell walls or inhibiting bacterial enzyme activity. Some examples of antibacterial agents that are commonly used in hydrogels include silver nanoparticles, chitosan, and quaternary ammonium compounds. Antibacterial hydrogels have a wide range of applications, including wound dressings, catheters, and medical implants. They can help to prevent infections, reduce inflammation, and promote tissue healing. In addition, they can be designed with specific properties to suit different applications, such as high mechanical strength or controlled release of antibacterial agents over time. Hydrogel wound dressings have come a long way in recent years, and the future looks very promising for these innovative wound care products. Overall, the future of hydrogel wound dressings is very promising, and we can expect to see continued innovation and advancement in this field in the years to come.

摘要

抗菌水凝胶是一种旨在抑制细菌生长和预防感染的水凝胶。这些水凝胶通常含有抗菌剂,这些抗菌剂可以整合到聚合物网络中,也可以涂覆在水凝胶的表面。这些水凝胶中的抗菌剂可以通过多种机制发挥作用,例如破坏细菌细胞壁或抑制细菌酶活性。在水凝胶中常用的抗菌剂的一些例子包括银纳米粒子、壳聚糖和季铵化合物。抗菌水凝胶有广泛的应用,包括伤口敷料、导管和医疗植入物。它们有助于预防感染、减少炎症和促进组织愈合。此外,它们可以设计成具有特定的性质,以适应不同的应用,例如高机械强度或随时间控制抗菌剂的释放。近年来,水凝胶伤口敷料已经取得了很大的进展,这些创新的伤口护理产品的未来前景非常广阔。总的来说,水凝胶伤口敷料的未来非常有希望,我们可以期待在未来几年看到这个领域的持续创新和进步。

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