Venulet J
Int J Clin Pharmacol Ther Toxicol. 1986 Jul;24(7):385-9.
Information about adverse drug reactions (ADR) helps the practicing physician to optimize his pharmacotherapy, however, he also generates most of the original observations and thus he is largely responsible for the quality of ADR data. As direct communication from physician to physician is limited other means had to be developed such as scientific papers, communication from health authorities and from the pharmaceutical industry. The paper discusses the characteristics of the elements involved in the process of generating assessing and disseminating ADR data and of their interplay.
关于药物不良反应（ADR）的信息有助于执业医师优化其药物治疗方案，然而，大多数原始观察结果也是由医师做出的，因此，ADR数据的质量很大程度上由医师负责。由于医师之间的直接交流有限，因此必须开发其他方式，如科学论文、卫生当局和制药行业的交流。本文讨论了ADR数据生成、评估和传播过程中各要素的特点及其相互作用。
