Sorrentino P, Rabuffo G, Baselice F, Troisi Lopez E, Liparoti M, Quarantelli M, Sorrentino G, Bernard C, Jirsa V
Institut de Neurosciences des Systèmes, Aix-Marseille University, Marseille, France.
Institute of Applied Sciences and Intelligent Systems, National Research Council, Pozzuoli, Italy.
Netw Neurosci. 2023 Jan 1;7(1):73-85. doi: 10.1162/netn_a_00270. eCollection 2023.
The functional organization of the brain is usually presented with a back-to-front gradient of timescales, reflecting regional specialization with sensory areas (back) processing information faster than associative areas (front), which perform information integration. However, cognitive processes require not only local information processing but also coordinated activity across regions. Using magnetoencephalography recordings, we find that the functional connectivity at the edge level (between two regions) is also characterized by a back-to-front gradient of timescales following that of the regional gradient. Unexpectedly, we demonstrate a reverse front-to-back gradient when nonlocal interactions are prominent. Thus, the timescales are dynamic and can switch between back-to-front and front-to-back patterns.
大脑的功能组织通常呈现出从后到前的时间尺度梯度，这反映了区域专业化，即感觉区域（后部）比执行信息整合的联合区域（前部）更快地处理信息。然而，认知过程不仅需要局部信息处理，还需要跨区域的协调活动。通过脑磁图记录，我们发现边缘水平（两个区域之间）的功能连接也具有与区域梯度一致的从后到前的时间尺度梯度。出乎意料的是，当非局部相互作用显著时，我们证明了存在从前往后的反向梯度。因此，时间尺度是动态的，可以在从后到前和从前往后的模式之间切换。
