Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi, P.R. China.
Chongqing Three Gorges Medical College, Chong Qing Shi, Feng Jie Xian, P.R. China.
Medicine (Baltimore). 2023 May 19;102(20):e33812. doi: 10.1097/MD.0000000000033812.
Gastric mucosal ulcer caused by drug overdose is very rare in clinical practice, and here is a case of gastric antral ulcer caused by drug overdose.
A 35-year-old housewife from a mountainous region in China took 48 Ibuprofen Sustained-Release capsules (300 mg/capsule) orally at 1 time. Because of severe tingling in the upper abdomen accompanied by a sharp increase in blood pressure, she came to the doctor 48 hours later.
Gastric antral ulcer (multiple stage A1), duodenococcitis, chronic nonatrophic gastritis, Helicobacter pylori infection, moderate depression, and cognitive impairment.
Acid suppression, antihypertensive and a series of symptomatic treatments.
All somatic symptoms disappeared after a follow-up visit 2 months later.
This case provides valuable information to the clinic, through the compilation of literature and case analysis, the author found that paying attention to mental health, to women in poor areas and to women from families of low education level are indispensable in medical diagnosis and treatment.
药物过量导致的胃黏膜溃疡在临床实践中非常罕见，本文报道了 1 例因药物过量导致的胃窦溃疡病例。
中国山区的 1 名 35 岁家庭主妇一次性口服了 48 粒布洛芬缓释胶囊（每粒 300mg）。因上腹部严重刺痛伴血压急剧升高，她在 48 小时后来就诊。
胃窦溃疡（多阶段 A1）、十二指肠炎、慢性非萎缩性胃炎、幽门螺杆菌感染、中度抑郁和认知障碍。
抑酸、降压及一系列对症治疗。
2 个月后随访时所有躯体症状消失。
该病例为临床提供了有价值的信息，通过文献汇编和病例分析，作者发现关注心理健康、贫困地区的女性和低教育水平家庭的女性在医疗诊断和治疗中必不可少。
