Department of Nutrition Biology, Central University of Haryana, Mahendragarh, India.
Dev Psychobiol. 2023 Jul;65(5):e22404. doi: 10.1002/dev.22404.
"Psychobiotics" are a novel class of probiotics that are beneficial to the health and functional efficiency of our brain and psychology. The main hold on command in ill conditions of the brain and psychology is overtaken by these psychobiotic bacteria (a dietary supplement) via the action/determined role of bacterial neurochemicals or neuroactive substances that are released by them in the intestinal epithelium after their ingestion. Although these psychobiotics flourish in the gut of the host consuming them, the effect is widely spread to the brain due to the communication between the gut and the brain via the bidirectional gut-brain axis. The nervous system involved in this directional process includes both the enteric nervous system and the central nervous system. With time, several corroborations have proved the effectiveness of psychobiotics in terms of mental illnesses and brain disorders. In the prevailing situation of the coronavirus pandemic, psychobiotics may serve as an aid because a majority of the population worldwide is already suffering from psychological issues due to changes in lifestyle and dietary habits, and in need of an immediate solution to cope with it. Moreover, the in silico approach is also vital for the development of biological relevance to neurosubstances.
“心理益生菌”是一类新型益生菌，有益于大脑和心理的健康和功能效率。在大脑和心理的不适条件下，这些心理益生菌（一种膳食补充剂）通过其在摄入后在肠上皮细胞中释放的细菌神经化学物质或神经活性物质的作用/确定作用来占据主导地位。尽管这些心理益生菌在食用它们的宿主的肠道中大量繁殖，但由于通过双向肠道-大脑轴在肠道和大脑之间进行的通信，其影响广泛传播到大脑。涉及这个方向过程的神经系统包括肠神经系统和中枢神经系统。随着时间的推移，已经有几项证实了心理益生菌在精神疾病和大脑障碍方面的有效性。在当前的冠状病毒大流行情况下，心理益生菌可能会起到辅助作用，因为由于生活方式和饮食习惯的改变，全世界大多数人已经患有心理问题，他们需要一个即时的解决方案来应对。此外，计算方法对于神经物质的生物学相关性的发展也至关重要。
