Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Pharmacology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul, Turkey.
J Mol Neurosci. 2022 Sep;72(9):1952-1964. doi: 10.1007/s12031-022-02053-3. Epub 2022 Jul 18.
Nervous system disorders are one of the common problems that affect many people around the world every year. Regarding the beneficial effects of the probiotics on the gut and the gut-brain axis, their application along with current medications has been the subject of intense interest. Psychobiotics are a probiotic strain capable to affect the gut-brain axis. The effective role of Psychobiotics in several neurological disorders is documented. Consumption of the Psychobiotics containing nutrients has positive effects on the improvement of microbiota as well as alleviation of some symptoms of central nervous system (CNS) disorders. In the present study, the effects of probiotic strains on some CNS disorders in terms of controlling the disease symptoms were reviewed. Finding suggests that Psychobiotics can efficiently alleviate the symptoms of several CNS disorders such as autism spectrum disorders, Parkinson's disease, multiple sclerosis, insomnia, depression, diabetic neuropathy, and anorexia nervosa. It can be concluded that functional foods containing psychotropic strains can help to improve mental health.
神经系统疾病是每年影响全球许多人的常见问题之一。关于益生菌对肠道和肠脑轴的有益影响，它们与现有药物一起应用已成为人们强烈关注的话题。益生菌是一种能够影响肠脑轴的益生菌菌株。益生菌在几种神经疾病中的有效作用已有记载。含有营养物质的益生菌的摄入对改善微生物群以及缓解中枢神经系统 (CNS) 疾病的一些症状有积极作用。在本研究中，综述了益生菌菌株对某些 CNS 疾病的影响，以控制疾病症状。研究结果表明，益生菌可有效缓解自闭症谱系障碍、帕金森病、多发性硬化症、失眠、抑郁、糖尿病性神经病和神经性厌食症等几种 CNS 疾病的症状。可以得出结论，含有精神药物菌株的功能性食品有助于改善心理健康。
