Pediatric Cardiology, Gazi University Faculty of Medicine, Ankara, Turkey.
Pediatrics, Gazi University Faculty of Medicine, Ankara, Turkey.
Cardiol Young. 2024 Jan;34(1):11-17. doi: 10.1017/S104795112300166X. Epub 2023 Jun 21.
Aortic/arterial stiffness is a reliable, independent predictor and a risk factor for cardiovascular mortality. Arterial stiffness is assessed by pulse wave velocity and echocardiography. The purpose of this study is to analyse aortic/arterial stiffness in patients using echocardiographic and pulse wave velocity techniques.
The participants of this study consisted of 62 patients who presented to the Gazi University Pediatric Endocrinology and Pediatric Cardiology outpatient clinics, including 21 obese, 20 overweight, and 21 normal-weight patients. Echocardiography was performed on all patients, and echocardiographic measurements were compared to pulse wave velocity measurements.
The mean (min-max) arterial strain measurements were 0.146 ± 0.0 (0.06-0.3) in the obese group and 0.106 ± 0.0 (0.05-0.18) in the overweight group. In comparison to the overweight group, the obese group had greater arterial strain measurements. The pulse wave velocity measurements in the obese and overweight groups were greater than those in the normal weight group (p > 0.05). Elastic modulus and aortic stiffness ß index values were shown to be positively correlated with pulse wave velocity measurements in the obese group (r = 0.56, r = 0.53, respectively; p = 0.008, p = 0.01, respectively). Systolic and diastolic blood pressure measurements were correlated with pulse wave velocity measurements in the obese group (r = 0.98, p = 0.0001, respectively).
In our study, echocardiographic aortic measurements showing the vessel wall were correlated with pulse wave velocity measurements. Echocardiographic evaluation should be included in the routine follow-up of patients because pulse wave velocity measurement devices are not available in all centres, echocardiography is available in many centres, it is easily applicable, and it facilitates the follow-up of patients.
主动脉/动脉僵硬度是心血管死亡率的可靠、独立预测因子和危险因素。动脉僵硬度通过脉搏波速度和超声心动图来评估。本研究的目的是使用超声心动图和脉搏波速度技术分析患者的主动脉/动脉僵硬度。
该研究的参与者包括 62 名就诊于加济大学儿科内分泌科和儿科心脏病科门诊的患者，其中 21 名肥胖，20 名超重，21 名体重正常。对所有患者进行超声心动图检查，并将超声心动图测量值与脉搏波速度测量值进行比较。
肥胖组的平均（最小-最大）动脉应变测量值为 0.146±0.0（0.06-0.3），超重组为 0.106±0.0（0.05-0.18）。与超重组相比，肥胖组的动脉应变测量值更大。肥胖组和超重组的脉搏波速度测量值均大于体重正常组（p＞0.05）。肥胖组的弹性模量和主动脉僵硬度β指数值与脉搏波速度测量值呈正相关（r=0.56，r=0.53，p=0.008，p=0.01）。肥胖组的收缩压和舒张压测量值与脉搏波速度测量值呈正相关（r=0.98，p=0.0001）。
在我们的研究中，显示血管壁的超声心动图主动脉测量值与脉搏波速度测量值相关。由于并非所有中心都有脉搏波速度测量设备，而超声心动图在许多中心都可用，易于应用，并且便于患者随访，因此应将超声心动图评估纳入患者的常规随访中。
