Division of Women's Health, Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Division of Hematology/Oncology, Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.
Drugs Aging. 2023 Aug;40(8):675-683. doi: 10.1007/s40266-023-01043-3. Epub 2023 Jun 21.
Menopause occurs in all women. During the menopause transition, 80% of women experience vasomotor symptoms that can last an average of 7-10 years or longer, sometimes into the seventh and eighth decades of life. Understanding how to manage vasomotor symptoms (VMS) in older menopausal women is important since these symptoms can negatively impact quality of life. This review provides a practical guide on how to approach VMS treatment either with menopausal hormone therapy or non-hormone options. When initiating, as well as continuing hormone therapy, the factors clinicians should consider as they weigh risks and benefits include assessing a woman's risks related to cardiovascular disease, breast cancer, and osteoporosis. Utilizing a shared decision-making approach in regard to menopausal symptom management should aim to support women and help them maintain health and quality of life.
绝经发生于所有女性。在绝经过渡期间,80%的女性会经历血管舒缩症状,这些症状平均持续 7-10 年或更长时间,有时会持续到生命的第七和第八个十年。了解如何管理老年绝经后女性的血管舒缩症状(VMS)很重要,因为这些症状会对生活质量产生负面影响。本综述提供了关于如何使用绝经激素治疗或非激素选择来治疗 VMS 的实用指南。在开始和继续激素治疗时,临床医生在权衡风险和益处时应考虑的因素包括评估女性与心血管疾病、乳腺癌和骨质疏松症相关的风险。在绝经症状管理方面,采用共同决策方法应旨在支持女性并帮助她们保持健康和生活质量。