Department of Infectology and Geographical Medicine, Center for Treatment of HIV/AIDS Patients, Academic L. Derer's University Hospital, Bratislava, Slovakia.
Third Faculty of Medicine, Charles University.
AIDS. 2023 Oct 1;37(12):1811-1818. doi: 10.1097/QAD.0000000000003633. Epub 2023 Jul 3.
Over 480 000 Ukrainian refugees have arrived in the Czech Republic since the Russian invasion of Ukraine in 2022, including over 500 people with HIV. This study describes the demographics, characteristics, and management of Ukrainian refugees with HIV in the Czech Republic.
Retrospective, observational, noninterventional study.
Ukrainian nationals registering at HIV centers in the Czech Republic with war refugee status were included. Data were collected from medical records between 1 March and 31 July 2022. The study was registered with the Czech State Institute for Drug Control, ID number 2301200000.
Four hundred and eighty-two patients were included in the study. Most patients were female (69.5%; n = 335/482) with well-controlled HIV. The median [interquartile range] CD4 + cell count was 597 [397] cells/μl of blood, and 79.3% ( n = 361/455) of patients had HIV RNA <40 copies/ml. Coinfections of hepatitis C virus, hepatitis B virus, and/or tuberculosis were reported for 17.4% ( n = 78/449), 9% ( n = 40/446) and 1.3% ( n = 6/446) of patients, respectively. In Ukraine, 85.7% ( n = 384/448) of patients had been receiving an integrase strand transfer inhibitor-based regimen and most (69.7%; n = 310/445) did not switch therapy upon arrival in the Czech Republic.
Migration from Ukraine is changing the characteristics of HIV epidemiology in the Czech Republic. Ukrainian refugees with HIV have been provided with a high standard of medical care in the Czech Republic. Improved coordination between medical services within the Czech Republic and between countries in the European Union is necessary to optimize patient care.
自 2022 年俄罗斯入侵乌克兰以来,已有超过 48 万乌克兰难民抵达捷克共和国,其中包括 500 多名艾滋病毒感染者。本研究描述了捷克共和国艾滋病毒感染者的乌克兰难民的人口统计学、特征和管理情况。
回顾性、观察性、非干预性研究。
本研究纳入在捷克共和国艾滋病毒中心注册并具有战争难民身份的乌克兰国民。数据于 2022 年 3 月 1 日至 7 月 31 日期间从病历中收集。本研究在捷克国家药物管制研究所注册,编号为 2301200000。
本研究共纳入 482 名患者。大多数患者为女性(69.5%;n = 335/482),艾滋病毒得到了很好的控制。中位数[四分位间距]CD4+细胞计数为 597[397]个细胞/μl 血液,79.3%(n = 361/455)的患者艾滋病毒 RNA <40 拷贝/ml。报告丙型肝炎病毒、乙型肝炎病毒和/或结核病合并感染的患者分别占 17.4%(n = 78/449)、9%(n = 40/446)和 1.3%(n = 6/446)。在乌克兰,85.7%(n = 384/448)的患者正在接受整合酶链转移抑制剂为基础的治疗方案,大多数(69.7%;n = 310/445)在抵达捷克共和国后未更换治疗方案。
从乌克兰的移民正在改变捷克共和国艾滋病毒流行情况的特征。捷克共和国为艾滋病毒感染者的乌克兰难民提供了高标准的医疗服务。需要改善捷克共和国境内医疗服务之间以及欧盟国家之间的协调,以优化患者护理。