Service de biologie clinique, hôpital Foch, Suresnes, France.
Service de Microbiologie Clinique, Groupe Hospitalier Paris Seine Saint-Denis, AP-HP, Bobigny, France.
Diagn Microbiol Infect Dis. 2023 Sep;107(1):116002. doi: 10.1016/j.diagmicrobio.2023.116002. Epub 2023 Jun 8.
The COVID-19 pandemic has strongly impacted healthcare settings. We assess changes in blood culture practices and results during the COVID-19 era. All blood culture vials processed between January 1, 2017, and December 31, 2020, by 3 clinical laboratories were included. A baseline period from January 1, 2017 to December 31, 2019, was compared to the year 2020. COVID-19 "waves" were defined as follows: "wave 1" from March 16 to May 10, 2020, and "wave 2" from October 29 to December 14, 2020. A mean of 143.5 and 158.6 vials per day were processed in 2019 and 2020 respectively. Up to 300 and 220 vials per day were processed during waves 1 and 2. Among positive vials, a higher rate of contaminant was noticed during wave 1 (55.9% vs 45.0%; P < 0.0001) and interwave (46.0% vs 38.6%; P < 0.0001) in comparison to previous years. The prevalence of contaminants returned to the baseline level during wave 2. Streptococcus pneumonia prevalence fell in 2020 in comparison to the baseline (0.4% vs 1.4%; P < 0.0001). The COVID-19 pandemic was associated with an increase in the number of blood culture vials processed, the rate of contaminants, and a fall in the number of pneumococcal bloodstream infections.
新型冠状病毒肺炎疫情对医疗机构产生了重大影响。我们评估了在新型冠状病毒肺炎疫情期间血培养实践和结果的变化。纳入了 3 家临床实验室于 2017 年 1 月 1 日至 2020 年 12 月 31 日期间处理的所有血培养瓶。将 2017 年 1 月 1 日至 2019 年 12 月 31 日设为基线期，并与 2020 年进行比较。将新型冠状病毒肺炎“波”定义为：“波 1”为 2020 年 3 月 16 日至 5 月 10 日，“波 2”为 2020 年 10 月 29 日至 12 月 14 日。2019 年和 2020 年每天分别处理 143.5 和 158.6 个培养瓶。在波 1 和波 2 期间，每天处理多达 300 和 220 个培养瓶。在阳性培养瓶中，与前几年相比，波 1（55.9%比 45.0%；P<0.0001）和波间（46.0%比 38.6%；P<0.0001）时污染率更高。在波 2 期间，污染率恢复到基线水平。与基线相比，2020 年肺炎链球菌的患病率下降（0.4%比 1.4%；P<0.0001）。新型冠状病毒肺炎大流行与血培养瓶处理数量的增加、污染率的增加以及肺炎链球菌血流感染数量的减少有关。
