IVIRMA Global Research Alliance, IVI Foundation, Instituto de Investigación Sanitaria La Fe (IIS La Fe), Valencia, Spain; IVIRMA Global Research Alliance, IVIRMA Valencia, Valencia, Spain.
IVIRMA Global Research Alliance, IVI Foundation, Instituto de Investigación Sanitaria La Fe (IIS La Fe), Valencia, Spain; IVIRMA Global Research Alliance, IVIRMA Valencia, Valencia, Spain.
Fertil Steril. 2023 Aug;120(2):218-227. doi: 10.1016/j.fertnstert.2023.06.015. Epub 2023 Jun 25.
Time-lapse imaging (TLI) allows continuous monitoring of embryo development without disturbing culture conditions by removing embryos from the incubator. The study of embryo kinetics using TLI has given rise to some new markers for embryo selection that are able to document and evaluate embryo morphology and the timing of developmental events through continuous live image tracking. Time-lapse imaging has emerged as a powerful tool for creating predictive models of in vitro fertilization outcomes. Fourty-seven articles were included in the present review to investigate the current situation of TLI in in vitro fertilization laboratories. Morphokinetics of the embryo during its in vitro development have been described using parameters indicative of the different events capable of predicting the ability to reach blastocyst stage, implantation and pregnancy rates, live birth outcome, and embryo ploidy.
延时成像（TLI）允许在不干扰培养条件的情况下通过将胚胎从孵化器中取出，从而对胚胎发育进行连续监测。使用 TLI 研究胚胎动力学已经产生了一些新的胚胎选择标记物，这些标记物能够通过连续的实时图像跟踪记录和评估胚胎形态和发育事件的时间。延时成像已经成为创建体外受精结果预测模型的强大工具。本综述纳入了 47 篇文章，旨在调查 TLI 在体外受精实验室中的现状。胚胎在体外发育过程中的形态动力学已使用能够预测到达囊胚阶段、着床和妊娠率、活产结局和胚胎倍性能力的不同事件的指标进行描述。
