Nguyen Tena, Tracy Katharine, Ullah Asad, Karim Nagla Abdel
Medical College of Georgia, Augusta University, Augusta, GA 30904, USA.
Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Clin Pract. 2023 Jun 13;13(3):715-730. doi: 10.3390/clinpract13030065.
Advanced-stage lung cancer (LC) causes significant morbidity and impacts patients' quality of life (QoL). Exercise has been proven to be safe, feasible, and beneficial for symptom reduction and QoL improvement in many types of cancers, but research is limited in advanced-stage LC patients. This systematic review evaluates the effect of exercise interventions on the symptoms and QoL in patients with advanced-stage LC. Twelve prospective studies (744 participants) were included, evaluating different combinations of exercises and training such as aerobics, tai chi, strength, inspiratory muscle training, and relaxation. Studies found outcomes including but not limited to improved QoL, symptom burden, psychosocial health, functional status, and physical function. The results of this review support that exercise is safe and feasible with evidence supporting improved QoL and symptom mitigation. Integration of exercise should be considered in the individualized management of advanced-stage LC patients under the guidance of their healthcare providers.
晚期肺癌（LC）会导致严重的发病率，并影响患者的生活质量（QoL）。运动已被证明对多种癌症患者减轻症状和改善生活质量是安全、可行且有益的，但针对晚期肺癌患者的研究有限。本系统评价评估了运动干预对晚期肺癌患者症状和生活质量的影响。纳入了12项前瞻性研究（744名参与者），评估了有氧运动、太极拳、力量训练、吸气肌训练和放松等不同运动和训练的组合。研究发现的结果包括但不限于生活质量改善、症状负担减轻、心理社会健康改善、功能状态改善和身体功能改善。本评价结果支持运动是安全可行的，有证据表明运动可改善生活质量并减轻症状。在医疗保健提供者的指导下，应考虑将运动纳入晚期肺癌患者的个体化管理中。
