Bade Brett C, Brooks Mary C, Nietert Sloan B, Ulmer Ansley, Thomas D David, Nietert Paul J, Scott JoAnn B, Silvestri Gerard A
1 Medical University of South Carolina (MUSC), Charleston, SC, USA.
2 Academic Magnet High School, North Charleston, SC, USA.
Integr Cancer Ther. 2018 Mar;17(1):73-79. doi: 10.1177/1534735416684016. Epub 2016 Dec 27.
Increasing physical activity (PA) is safe and beneficial in lung cancer (LC) patients. Advanced-stage LC patients are under-studied and have worse symptoms and quality of life (QoL). We evaluated the feasibility of monitoring step count in advanced LC as well as potential correlations between PA and QoL.
This is a prospective, observational study of 39 consecutive patients with advanced-stage LC. Daily step count over 1 week (via Fitbit Zip), QoL, dyspnea, and depression scores were collected. Spearman rank testing was used to assess correlations. Correlation coefficients (ρ) >0.3 or <-0.3 (more and less correlated, respectively) were considered potentially clinically significant.
Most (83%) of the patients were interested in participating, and 67% of those enrolled were adherent with the device. Of those using the device (n = 30), the average daily step count was 4877 (range = 504-12 118) steps/d. Higher average daily step count correlated with higher QoL (ρ = 0.46), physical (ρ = 0.61), role (ρ = 0.48), and emotional functioning (ρ = 0.40) scores as well as lower depression (ρ = -0.40), dyspnea (ρ = -0.54), and pain (ρ = -0.37) scores.
Remote PA monitoring (Fitbit Zip) is feasible in advanced-stage LC patients. Interest in participating in this PA study was high with comparable adherence to other PA studies. In those utilizing the device, higher step count correlates with higher QoL as well as lower dyspnea, pain, and depression scores. PA monitoring with wearable devices in advanced-stage LC deserves further study.
增加身体活动（PA）对肺癌（LC）患者是安全且有益的。晚期LC患者的相关研究较少，且症状更严重，生活质量（QoL）更差。我们评估了监测晚期LC患者步数的可行性以及PA与QoL之间的潜在相关性。
这是一项对39例连续的晚期LC患者进行的前瞻性观察性研究。收集了1周内的每日步数（通过Fitbit Zip）、QoL、呼吸困难和抑郁评分。采用Spearman秩检验评估相关性。相关系数（ρ）>0.3或<-0.3（分别表示相关性较高和较低）被认为可能具有临床意义。
大多数（83%）患者有兴趣参与，67%的入组患者坚持使用该设备。在使用该设备的患者中（n = 30），平均每日步数为4877步/天（范围 = 504 - 12118步/天）。较高的平均每日步数与较高的QoL（ρ = 0.46）、身体功能（ρ = 0.61）、角色功能（ρ = 0.48）和情感功能（ρ = 0.40）评分以及较低的抑郁（ρ = -0.40）、呼吸困难（ρ = -0.54）和疼痛（ρ = -0.37）评分相关。
远程PA监测（Fitbit Zip）在晚期LC患者中是可行的。参与这项PA研究的兴趣较高，与其他PA研究的依从性相当。在使用该设备的患者中，步数增加与较高的QoL以及较低的呼吸困难、疼痛和抑郁评分相关。晚期LC患者使用可穿戴设备进行PA监测值得进一步研究。
