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法国腹部手术后切口疝修补的发生率、风险因素和负担:一项全国性研究。

Incidence, risk factors, and burden of incisional hernia repair after abdominal surgery in France: a nationwide study.

机构信息

Service de Chirurgie Générale, Digestive, Cancérologique et Urgences, CHU de Dijon - CR INSERM 1231 - CIC 1432, Module Épidémiologie Clinique - Université de Bourgogne, 14, rue Paul Gaffarel, 21079, Dijon Cedex, France.

Service de Chirurgie Générale, Digestive et Endocrinienne, CHU de Reims, Reims, France.

出版信息

Hernia. 2023 Aug;27(4):861-871. doi: 10.1007/s10029-023-02825-9. Epub 2023 Jun 27.

Abstract

PURPOSE

Incisional hernias are common after laparotomies. The aims of this study were to assess the rate of incisional hernia repair after abdominal surgery, recurrence rate, hospital costs, and risk factors, in France.

METHODS

This national, retrospective, longitudinal, observational study was based on the exhaustive hospital discharge database (PMSI). All adult patients (≥ 18 years old) hospitalised for an abdominal surgical procedure between 01-01-2013 and 31-12-2014 and hospitalised for incisional hernia repair within five years were included. Descriptive analyses and cost analyses from the National Health Insurance (NHI) viewpoint (hospital care for the hernia repair) were performed. To identify risk factors for hernia repair a multivariable Cox model and a machine learning analysis were performed.

RESULTS

In 2013-2014, 710074 patients underwent abdominal surgery, of which 32633 (4.6%) and 5117 (0.7%) had ≥ 1 and ≥ 2 incisional hernia repair(s) within five years, respectively. Mean hospital costs amounted to €4153/hernia repair, representing nearly €67.7 million/year. Some surgical sites exposed patients at high risk of incisional hernia repair: colon and rectum (hazard ratio [HR] 1.2), and other sites on the small bowel and the peritoneum (HR 1.4). Laparotomy procedure and being ≥ 40 years old put patients at high risk of incisional hernia repair even when operated on low-risk sites such as stomach, duodenum, and hepatobiliary.

CONCLUSION

The burden of incisional hernia repair is high and most patients are at risk either due to age ≥ 40 or the surgery site. New approaches to prevent the onset of incisional hernia are warranted.

摘要

目的

剖腹手术后常发生切口疝。本研究旨在评估法国腹部手术后切口疝修补的发生率、复发率、住院费用和危险因素。

方法

这是一项全国性的回顾性纵向观察研究,基于详尽的医院出院数据库(PMSI)。纳入 2013 年 1 月 1 日至 2014 年 12 月 31 日期间因腹部手术住院且在五年内接受切口疝修补的所有成年患者(≥18 岁)。进行描述性分析和从国民健康保险(NHI)角度进行成本分析(疝修补的住院护理)。为了确定疝修补的危险因素,进行了多变量 Cox 模型和机器学习分析。

结果

2013-2014 年,710074 例患者接受了腹部手术,其中 32633 例(4.6%)和 5117 例(0.7%)在五年内至少进行了 1 次和≥2 次切口疝修补。平均住院费用为 4153 欧元/疝修补,每年近 6770 万欧元。一些手术部位使患者面临切口疝修补的高风险:结肠和直肠(风险比[HR]1.2),以及小肠和腹膜的其他部位(HR 1.4)。剖腹手术和年龄≥40 岁使患者即使在接受低风险部位(如胃、十二指肠和肝胆)手术时也面临切口疝修补的高风险。

结论

切口疝修补的负担很重,大多数患者要么因年龄≥40 岁,要么因手术部位而面临风险。需要采取新的方法来预防切口疝的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/10374769/41d2bccaad24/10029_2023_2825_Fig1_HTML.jpg

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