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食管穿孔的病因、转归和外科治疗的作用——18 年转诊中心外科治疗经验。

Esophageal perforation etiology, outcome, and the role of surgical management - an 18-year experience of surgical cases in a referral center.

机构信息

Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Science, Shiraz, Iran.

School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

BMC Surg. 2023 Jun 27;23(1):177. doi: 10.1186/s12893-023-02080-w.

DOI:10.1186/s12893-023-02080-w
PMID:37370071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10304640/
Abstract

INTRODUCTION

Esophageal perforation is a surgical emergency with a high rate of morbidity and mortality. Its poor prognosis is mainly associated with previous patient-specific comorbidities and a lack of timely diagnosis and treatment. The objective of this study was to investigate the etiological factors and different surgical methods of treatment with consideration of mortality rate and comorbidities.

METHOD

The present cross-sectional study was conducted on patients who underwent surgical intervention due to esophageal injury from 2002 to 2019 (18 years). Demographic and clinical characteristics along with performed surgical interventions were evaluated accordingly.

RESULTS

In this study, 69 patients with a mean age of 38.8 years were evaluated, of which 45 (65.2%) cases were men. In terms of location of the perforation, the thoracic portion of the esophagus followed by the cervical and abdominal esophagus were more frequently injured with a rate of 32 (46.4%), 30 (43.5%), and 19 (27.5%) cases, respectively. Accordingly, foreign body ingestion followed by penetrating injuries were the most common causative agents leading to esophageal perforation.

CONCLUSION

Obtaining the desired results from the treatment of this condition depends on factors such as patients' previous comorbidities, cause of the rupture, the location of the esophageal damage, and delay in the start of treatment. Since there is no single gold standard treatment strategy, each patient should be individually evaluated.

摘要

引言

食管穿孔是一种外科急症,其发病率和死亡率都很高。其预后不良主要与患者先前的特定合并症以及缺乏及时的诊断和治疗有关。本研究的目的是探讨与死亡率和合并症相关的病因因素和不同的治疗手术方法。

方法

本回顾性研究纳入了 2002 年至 2019 年(18 年)期间因食管损伤而接受手术干预的患者。对人口统计学和临床特征以及所进行的手术干预进行了评估。

结果

本研究共评估了 69 例平均年龄为 38.8 岁的患者,其中 45 例(65.2%)为男性。就穿孔部位而言,胸段食管其次是颈段和腹段食管更常受损,分别为 32 例(46.4%)、30 例(43.5%)和 19 例(27.5%)。相应地,异物摄入和穿透性损伤是导致食管穿孔的最常见原因。

结论

治疗这种疾病的效果取决于患者先前的合并症、破裂原因、食管损伤的位置以及治疗开始的延迟等因素。由于没有单一的金标准治疗策略,每个患者都应进行个体化评估。

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