Rosas Cancio-Suárez Marta, Alonso Cecilia, Vivancos María Jesús, Pérez-Elías María Jesús, Cárdenas María José, Vélez-Díaz-Pallarés Manuel, Corbacho María Dolores, Martín-Pedraza Laura, Muriel Alfonso, Martínez-Sanz Javier, Moreno Santiago
Department of Infectious Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Carretera de Colmenar Km 9.1, 28034 Madrid, Spain.
CIBERINFEC, 28029 Madrid, Spain.
J Clin Med. 2023 Jun 7;12(12):3882. doi: 10.3390/jcm12123882.
The COVID-19 pandemic and associated lockdown measures have been associated with substantial disruptions to health care services, including screening for human immunodeficiency virus (HIV) and management of people living with HIV (PLWH). Data from 3265 patients were examined in a retrospective cohort study. We compared outpatient follow-up for PLWH, the number of new patients, treatment adherence, hospitalizations, and deaths during the "pandemic period" (March 2020 to February 2021), the "pre-pandemic period" (the equivalent time frame in 2019), and the "post-pandemic period" (March to September 2021). During the pandemic period, the number of new patients seen at the HIV clinic (116) as well as the requested viral load tests (2414) decreased significantly compared to the pre-pandemic (204 and 2831, respectively) and post-pandemic periods (146 and 2640, respectively) ( < 0.01 for all the comparisons). However, across the three study periods, the number of drug refills (1385, 1330, and 1411, respectively), the number of patients with undetectable viral loads (85%, 90%, and 93%, respectively), and the number of hospital admissions among PLWH remained constant. Despite the COVID-19 pandemic's impact, our findings show stability in the retention of clinical care, adherence to treatment, and viral suppression of PLWH, with no significant impact on hospitalization rates or all-cause mortality.
2019冠状病毒病疫情及相关封锁措施对医疗服务造成了重大干扰，包括人类免疫缺陷病毒（HIV）筛查和HIV感染者（PLWH）的管理。在一项回顾性队列研究中，对3265例患者的数据进行了检查。我们比较了“疫情期间”（2020年3月至2021年2月）、“疫情前时期”（2019年的相同时间框架）和“疫情后时期”（2021年3月至9月）PLWH的门诊随访情况、新患者数量、治疗依从性、住院情况和死亡情况。在疫情期间，与疫情前（分别为204例和2831例）和疫情后时期（分别为146例和2640例）相比，HIV诊所的新患者数量（116例）以及病毒载量检测需求（2414例）显著减少（所有比较均<0.01）。然而，在三个研究时期，药物续方数量（分别为1385例、1330例和1411例）、病毒载量不可检测的患者数量（分别为85%、90%和93%）以及PLWH的住院人数保持不变。尽管2019冠状病毒病疫情产生了影响，但我们的研究结果显示，PLWH的临床护理保留率、治疗依从性和病毒抑制情况保持稳定，对住院率或全因死亡率没有显著影响。
