Patwardhan Sushmita, Phan Jonathan, Smedile Francesco, Vetriani Costantino
Department of Marine and Coastal Sciences, Rutgers University, New Brunswick, NJ 08901, USA.
Department of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ 08901, USA.
Microorganisms. 2023 May 23;11(6):1366. doi: 10.3390/microorganisms11061366.
Varunaivibrio type strain TC8 is a mesophilic, facultatively anaerobic, facultatively chemolithoautotrophic alphaproteobacterium isolated from a sulfidic shallow-water marine gas vent located at Tor Caldara, Tyrrhenian Sea, Italy. belongs to the family within the Alphaproteobacteria, with as its closest relative. The genome of encodes the genes involved in sulfur, thiosulfate and sulfide oxidation, as well as nitrate and oxygen respiration. The genome encodes the genes involved in carbon fixation via the Calvin-Benson-Bassham cycle, in addition to genes involved in glycolysis and the TCA cycle, indicating a mixotrophic lifestyle. Genes involved in the detoxification of mercury and arsenate are also present. The genome also encodes a complete flagellar complex, one intact prophage and one CRISPR, as well as a putative DNA uptake mechanism mediated by the type IVc (aka Tad pilus) secretion system. Overall, the genome of highlights the organism's metabolic versatility, a characteristic that makes this strain well-adapted to the dynamic environmental conditions of sulfidic gas vents.
瓦鲁纳弧菌模式菌株TC8是一种嗜温、兼性厌氧、兼性化能自养型α-变形菌，从位于意大利第勒尼安海托尔卡尔达拉的一个含硫浅水海洋气体喷口分离得到。它属于α-变形菌纲中的 科，与 亲缘关系最近。瓦鲁纳弧菌的基因组编码参与硫、硫代硫酸盐和硫化物氧化以及硝酸盐和氧气呼吸的基因。该基因组除了编码参与糖酵解和三羧酸循环的基因外，还编码通过卡尔文-本森-巴斯姆循环参与碳固定的基因，表明其具有混合营养型生活方式。还存在参与汞和砷酸盐解毒的基因。该基因组还编码一个完整的鞭毛复合体、一个完整的原噬菌体和一个CRISPR，以及一种由IVc型（又名Tad菌毛）分泌系统介导的假定DNA摄取机制。总体而言，瓦鲁纳弧菌的基因组突出了该生物体的代谢多样性，这一特性使该菌株能够很好地适应含硫气体喷口的动态环境条件。
