Jawhara Samir
UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, Centre National de la Recherche Scientifique, F-59000 Lille, France.
Institut National de la Santé et de la Recherche Médicale U1285, University of Lille, F-59000 Lille, France.
Microorganisms. 2023 Jun 11;11(6):1556. doi: 10.3390/microorganisms11061556.
Western diets are rapidly spreading due to globalization, causing an increase in obesity and diseases of civilization. These Western diets are associated with changes in the gut microbiota related to intestinal inflammation. This review discusses the adverse effects of Western diets, which are high in fat and sugar and low in vegetable fiber, on the gut microbiota. This leads to gut dysbiosis and overgrowth of , which is a major cause of fungal infection worldwide. In addition to an unhealthy Western diet, other factors related to disease development and gut dysbiosis include smoking, excessive alcohol consumption, lack of physical activity, prolonged use of antibiotics, and chronic psychological stress. This review suggests that a diversified diet containing vegetable fiber, omega-3 polyunsaturated fatty acids, vitamins D and E, as well as micronutrients associated with probiotic or prebiotic supplements can improve the biodiversity of the microbiota, lead to short-chain fatty acid production, and reduce the abundance of fungal species in the gut. The review also discusses a variety of foods and plants that are effective against fungal overgrowth and gut dysbiosis in traditional medicine. Overall, healthy diets and lifestyle factors contribute to human well-being and increase the biodiversity of the gut microbiota, which positively modulates the brain and central nervous system.
由于全球化,西方饮食正在迅速传播,导致肥胖和文明病增加。这些西方饮食与肠道微生物群的变化有关,而肠道微生物群的变化与肠道炎症相关。本综述讨论了高脂肪、高糖和低膳食纤维的西方饮食对肠道微生物群的不良影响。这会导致肠道生态失调和白色念珠菌过度生长,白色念珠菌是全球真菌感染的主要原因。除了不健康的西方饮食外,与疾病发展和肠道生态失调相关的其他因素还包括吸烟、过量饮酒、缺乏体育活动、长期使用抗生素以及慢性心理压力。本综述表明,含有膳食纤维、ω-3多不饱和脂肪酸、维生素D和E以及与益生菌或益生元补充剂相关的微量营养素的多样化饮食可以改善微生物群的生物多样性,促进短链脂肪酸的产生,并减少肠道中真菌种类的丰度。该综述还讨论了传统医学中对真菌过度生长和肠道生态失调有效的各种食物和植物。总体而言,健康的饮食和生活方式因素有助于人类健康,并增加肠道微生物群的生物多样性,这对大脑和中枢神经系统具有积极的调节作用。