de Novais Diogo Pereira Silva, Batista Thiago Mafra, Costa Eduardo Almeida, Pirovani Carlos Priminho
Department of Biological Sciences, Center for Biotechnology and Genetics, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil.
Bahia Federal Institute of Education, Science and Technology (IFBA), Porto Seguro 45810-000, BA, Brazil.
Microorganisms. 2023 Jun 13;11(6):1567. doi: 10.3390/microorganisms11061567.
A set of diseases caused by fungi and oomycetes are responsible for large losses in annual world cocoa production. Managing the impact caused by these diseases is very complex because a common solution has yet to be found for different pathogens. In this context, the systematic knowledge of L. pathogens' molecular characteristics may help researchers understand the possibilities and limitations of cocoa disease management strategies. This work systematically organized and summarized the main findings of omics studies of eukaryotic pathogens, focusing on the plant-pathogen interaction and production dynamics. Using the PRISMA protocol and a semiautomated process, we selected papers from the Scopus and Web of Science databases and collected data from the selected papers. From the initial 3169 studies, 149 were selected. The first author's affiliations were mostly from two countries, Brazil (55%) and the USA (22%). The most frequent genera were (105 studies), (59 studies) and (13 studies). The systematic review database includes papers reporting the whole-genome sequence from six cocoa pathogens and evidence of some necrosis-inducing-like proteins, which are common in pathogen genomes. This review contributes to the knowledge about diseases, providing an integrated discussion of pathogens' molecular characteristics, common mechanisms of pathogenicity and how this knowledge is produced worldwide.
由真菌和卵菌引起的一系列疾病给全球可可年产量造成了巨大损失。应对这些疾病所造成的影响非常复杂，因为尚未找到针对不同病原体的通用解决方案。在这种情况下，系统了解病原体的分子特征可能有助于研究人员理解可可疾病管理策略的可能性和局限性。这项工作系统地组织并总结了真核病原体组学研究的主要发现，重点关注植物-病原体相互作用和生产动态。我们使用PRISMA协议和半自动化流程，从Scopus和Web of Science数据库中筛选论文，并从所选论文中收集数据。从最初的3169项研究中，选出了149项。第一作者的所属机构大多来自两个国家，巴西（55%）和美国（22%）。最常见的属是（105项研究）、（59项研究）和（13项研究）。该系统综述数据库包括报告六种可可病原体全基因组序列的论文，以及一些在病原体基因组中常见的坏死诱导样蛋白的证据。本综述有助于人们了解疾病，对病原体的分子特征、常见致病机制以及全球范围内如何产生这些知识进行综合讨论。
