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全基因组关联研究揭示与可可（L.）对 spp. 的生产力和抗病性相关的新候选基因

Genome-Wide Association Study Reveals Novel Candidate Genes Associated with Productivity and Disease Resistance to spp. in Cacao ( L.).

机构信息

Centro de Investigación Tibaitatá, Corporación Colombiana de Investigación Agropecuaria, Agrosavia, Bogotá, Colombia.

Centro de Investigación Turipaná Corporación Colombiana de Investigación Agropecuaria, Agrosavia, Montería, Colombia.

出版信息

G3 (Bethesda). 2020 May 4;10(5):1713-1725. doi: 10.1534/g3.120.401153.

DOI:10.1534/g3.120.401153
PMID:32169867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7202020/
Abstract

Cacao ( L.), the source of chocolate, is one of the most important commodity products worldwide that helps improve the economic livelihood of farmers. Diseases like frosty pod rot caused by and witches' broom caused by limit the cacao productivity, this can be solved by using resistant varieties. In the current study, we sequenced 229 cacao accessions using genotyping-by-sequencing to examine the genetic diversity and population structure employing 9,003 and 8,131 single nucleotide polymorphisms recovered by mapping against two cacao genomes (Criollo B97-61/B2 v2 and Matina 1-6 v1.1). In the phenotypic evaluation, three promising accessions for productivity and 10 with good tolerance to the frosty pod rot and witches' broom diseases were found. A genome-wide association study was performed on 102 accessions, discovering two genes associated with productivity and seven to disease resistance. The results enriched the knowledge of the genetic regions associated with important cacao traits that can have significant implications for conservation and breeding strategies like marker-assisted selection.

摘要

可可（L.）是巧克力的原料，是全球最重要的商品之一，有助于提高农民的经济生计。由 和 引起的霜疫霉病和丛枝病等疾病限制了可可的生产力，可以通过使用抗性品种来解决。在本研究中，我们使用基因分型测序对 229 个可可品系进行了测序，以利用在两个可可基因组（克里奥罗 B97-61/B2 v2 和马蒂纳 1-6 v1.1）上进行映射获得的 9,003 和 8,131 个单核苷酸多态性来检查遗传多样性和群体结构。在表型评估中，发现了三个具有生产力潜力的有希望的品系，以及 10 个对霜疫霉病和丛枝病具有良好耐受性的品系。对 102 个品系进行了全基因组关联研究，发现了两个与生产力相关的基因和七个与抗病性相关的基因。结果丰富了与重要可可性状相关的遗传区域的知识，这对保护和育种策略（如标记辅助选择）具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/17bb9ce44a4a/1713f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/66832f31c665/1713f1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/4fb88dfb9ce1/1713f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/68a762ecc455/1713f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/ba456186c12a/1713f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/17bb9ce44a4a/1713f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/66832f31c665/1713f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/cc61fb9b8552/1713f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/4fb88dfb9ce1/1713f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/68a762ecc455/1713f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/ba456186c12a/1713f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7a/7202020/17bb9ce44a4a/1713f6.jpg

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