Department of Obstetrics and Gynaecology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Nutrients. 2023 Jun 13;15(12):2733. doi: 10.3390/nu15122733.
Probiotics are live microorganisms that confer beneficial effects on human health when an adequate dose is administered. Recently, the use of probiotics has gained tremendous interest from the public due to its promising effects in the management of various reproductive diseases. However, the review of probiotics' benefits on benign gynaecological disorders, including vaginal infections, polycystic ovary syndrome (PCOS) and endometriosis, remains scarce. Therefore, this review is built on current knowledge on the beneficial effects of probiotics against selected benign gynaecological disorders. Recent findings point out that probiotics' supplementation in different clinical and in vivo models showed promising health effects and results in the amelioration of disease symptoms. Thus, in this review, we showed the findings of both studies performed in clinical settings and animal studies. However, current information, solely based on clinical trials or animal studies, is inadequate in communicating the excellent findings on the beneficial effects of probiotics on human health. Therefore, future clinical intervention studies are required to further elucidate the evidence of the benefits of probiotics benefits regarding these gynaecological disorders.
益生菌是活的微生物,当给予足够剂量时,会对人类健康产生有益的影响。最近,由于益生菌在治疗各种生殖疾病方面的前景,公众对其的兴趣大增。然而,关于益生菌对良性妇科疾病(包括阴道感染、多囊卵巢综合征(PCOS)和子宫内膜异位症)的益处的综述仍然很少。因此,本综述基于当前关于益生菌对选定良性妇科疾病的有益影响的知识。最近的研究结果表明,益生菌在不同的临床和体内模型中的补充显示出有希望的健康效果,并改善了疾病症状。因此,在本综述中,我们展示了在临床环境和动物研究中进行的研究结果。然而,仅基于临床试验或动物研究的现有信息不足以传达益生菌对人类健康有益影响的优异发现。因此,需要进行未来的临床干预研究,以进一步阐明益生菌对这些妇科疾病有益影响的证据。