Wang Xinyu, Jia Qian-Nan, Wu Mengyin, Liu Mingjuan, Li Jun
Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing 100730, China.
Vaccines (Basel). 2023 Jun 19;11(6):1113. doi: 10.3390/vaccines11061113.
Melanoma is a malignant tumor that originates from melanocytes and is known for its aggressive behavior and high metastatic potential. In recent years, vaccine therapy has emerged as a promising approach for the treatment of melanoma, offering targeted and individualized immunotherapy options. In this study, we conducted a bibliometric analysis to assess the global research trends and impact of publications related to melanoma and vaccine therapy.
We retrieved relevant literature from the Web of Science database from the past decade (2013-2023) using keywords such as "melanoma", "vaccine therapy", and "cancer vaccines". We used bibliometric indicators including publication trends, citation analysis, co-authorship analysis, and journal analysis to evaluate the research landscape of this field.
After screening, a total of 493 publications were included in the analysis. We found that melanoma and vaccine therapy have gained significant attention in the field of cancer immunotherapy, as evidenced by the numerous research output and increasing citation impact. The United States, China, and their organizations are the leading countries/institutes in terms of publication output, and collaborative research networks are prominent in this field. Clinical trials evaluating the safety and efficacy of vaccination treatment in melanoma patients are the focus of research.
This study provide valuable insights into the novel research landscape of vaccine treatment of melanoma, which could inform future research directions and facilitate knowledge exchange among researchers in this field.
黑色素瘤是一种起源于黑素细胞的恶性肿瘤，以其侵袭性和高转移潜能而闻名。近年来，疫苗疗法已成为治疗黑色素瘤的一种有前景的方法，提供了靶向和个体化的免疫治疗选择。在本研究中，我们进行了文献计量分析，以评估与黑色素瘤和疫苗疗法相关的全球研究趋势及出版物的影响力。
我们使用“黑色素瘤”“疫苗疗法”和“癌症疫苗”等关键词，从过去十年（2013 - 2023年）的科学网数据库中检索相关文献。我们使用文献计量指标，包括出版趋势、引文分析、共同作者分析和期刊分析，来评估该领域的研究格局。
经过筛选，共有493篇出版物纳入分析。我们发现，黑色素瘤和疫苗疗法在癌症免疫治疗领域受到了极大关注，众多的研究成果和不断增加的引文影响力就是证明。美国、中国及其机构在出版物产出方面是领先的国家/机构，并且协作研究网络在该领域很突出。评估黑色素瘤患者疫苗接种治疗安全性和有效性的临床试验是研究重点。
本研究为黑色素瘤疫苗治疗的新研究格局提供了有价值的见解，可为未来研究方向提供参考，并促进该领域研究人员之间的知识交流。
