Instituto de Medicina, Estudos e Desenvolvimento, Faculdade Meridional - Passo Fundo (RS), Brazil.
Universidade de São Paulo, Hospital Universitário, Centro de Pesquisa Clínica e Epidemiológica - São Paulo (SP), Brazil.
Rev Assoc Med Bras (1992). 2023 Jun 26;69(6):e20230038. doi: 10.1590/1806-9282.20230038. eCollection 2023.
This study investigated the association of psoriasis with cardiovascular risk factors and psychological aspects among participants of the Brazilian Longitudinal Study of Adult Health.
This is a cross-sectional study from the baseline data of the Brazilian Longitudinal Study of Adult Health cohort, collected between 2008 and 2010 in six state capitals of Brazil (i.e., Belo Horizonte, Porto Alegre, Rio de Janeiro, Salvador, São Paulo, and Vitória). Participants were active and retired civil servants from college and research institutions, aged between 35 and 74 years. Exclusion criteria included the intention to quit working at the institution, pregnancy, severe cognitive impairment, and, if retired, residence outside of a study center's corresponding area. Psoriasis case identification was based on a previous medical diagnosis of psoriasis. Cardiovascular risk profile, psychological aspects, and sociodemographic variables were investigated.
Data from 15,105 participants were analyzed (mean age of 52.3 years, 51.3% women). The prevalence of psoriasis was 1.6% (n=236). Psoriasis was associated with higher education (OR 1.94 [CI 1.07-3.52]), health insurance plan (OR 1.56 [CI 1.08-2.25]), central obesity (OR 1.63 [CI 1.10-2.40]), smoking status (former OR 1.40 [CI 1.03-1.88]; current OR 1.61 [CI 1.08-2.40]), and very bad self-perception of health (OR 7.22 [CI 2.41-21.64]), remaining significant even after multivariate adjustment. Self-reported Black participants were less likely to have psoriasis (OR 0.45 [CI 0.26-0.75]).
In a sample of healthy workers, psoriasis was associated with central obesity, smoking, and a very bad self-perception of health, which may contribute to future cardiovascular disease.
本研究旨在调查巴西成人健康纵向研究中的参与者中银屑病与心血管危险因素和心理方面的关系。
这是一项来自巴西成人健康纵向研究基线数据的横断面研究，于 2008 年至 2010 年在巴西六个州首府（贝洛奥里藏特、阿雷格里港、里约热内卢、萨尔瓦多、圣保罗和维多利亚）收集。参与者为大学和研究机构的在职和退休公务员，年龄在 35 至 74 岁之间。排除标准包括打算离开机构工作、怀孕、严重认知障碍以及如果退休，居住在研究中心相应区域之外。银屑病病例的识别基于既往银屑病的医学诊断。调查了心血管风险状况、心理方面和社会人口统计学变量。
对 15105 名参与者的数据进行了分析（平均年龄 52.3 岁，51.3%为女性）。银屑病的患病率为 1.6%（n=236）。银屑病与较高的教育程度（OR 1.94 [CI 1.07-3.52]）、健康保险计划（OR 1.56 [CI 1.08-2.25]）、中心性肥胖（OR 1.63 [CI 1.10-2.40]）、吸烟状况（既往 OR 1.40 [CI 1.03-1.88]；当前 OR 1.61 [CI 1.08-2.40]）和非常差的自我健康感知（OR 7.22 [CI 2.41-21.64]）相关，即使在多变量调整后仍有统计学意义。自报为黑人的参与者患银屑病的可能性较低（OR 0.45 [CI 0.26-0.75]）。
在健康工人样本中，银屑病与中心性肥胖、吸烟和非常差的自我健康感知有关，这可能导致未来的心血管疾病。
