Suppr超能文献

氧化锌丁香酚与不同浓度纳米姜黄素联合应用时的牙齿变色及溶解性:一项研究

Tooth Discoloration and Solubility of Zinc Oxide Eugenol Combined with Different Concentrations of Nano-Curcumin: An Study.

作者信息

Sahebalam Rasoul, Bagheri Hossein, Jafarzadeh Hamid, Khodkari Hamide, Ganjehzadeh Shabnam

机构信息

Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Dental Materials Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Dent (Shiraz). 2023 Jun;24(2):226-234. doi: 10.30476/dentjods.2022.92933.1687.

Abstract

STATEMENT OF THE PROBLEM

Due to the unfavorable properties of eugenol, the eugenol content can be reduced to improve the properties of zinc oxide eugenol (ZOE) by making a new combination of nanocurcumin called curcumin pulpal paste (CPP).

PURPOSE

The aim of this study was to evaluate the solubility and tooth discoloration of three concentrations of CPP compared to ZOE, and Metapex.

MATERIALS AND METHOD

In this study for evaluating of the solubility, five groups including ZOE, Metapex, and three concentrations of CPP (5%, 10%, and 20%) were tested. For evaluating the solubility, the changes in of the weight of samples were measured at 1, 3, 7 and 30 days after initial setting. In order to evaluate the tooth discoloration, 75 bovine maxillary anterior teeth were filled with one of five pulpal pastes. The changes in tooth color were evaluated at 1 hour, 1 week, 1 and 3 months after material placement.

RESULTS

The solubility increased by increasing the nano-curcumin percentage in CPPs. After 30 days, the solubility of the 5%CPP, and ZOE was not significantly different (= 1.000). According to the colorimetric test, after 3 months, the highest discoloration was recorded for 20% CPP (8.45), and the smallest discoloration was registered for Metapex (4.06). The discoloration of 5% CPP, and 10% CPP was similar to ZOE's color change (> 0.05).

CONCLUSION

The results of the present study showed that the solubility of pulpal paste has increased with increasing curcumin concentrations. Therefore, pulpal paste with different nanocurcumin concentrations can be used considering the patient's age and the desired time of deciduous tooth loss, and dissolution of pulpal paste. Concerning the discoloration after 3 months, Metapex was the best material and the most discoloration rate was related to 20% CPP, and there was no difference between the 5% CPP, and 10% CPP with ZOE.

摘要

问题陈述

由于丁香酚的不良特性,通过制备一种名为姜黄素牙髓糊剂(CPP)的新型纳米姜黄素组合,可以降低丁香酚含量以改善氧化锌丁香酚(ZOE)的性能。

目的

本研究的目的是评估与ZOE和Metapex相比,三种浓度的CPP的溶解度和牙齿变色情况。

材料与方法

在本研究中,为评估溶解度,测试了包括ZOE、Metapex和三种浓度的CPP(5%、10%和20%)在内的五组。为评估溶解度,在初始凝固后的1、3、7和30天测量样品重量的变化。为评估牙齿变色情况,用五种牙髓糊剂之一填充75颗牛上颌前牙。在材料放置后的1小时、1周、1个月和3个月评估牙齿颜色的变化。

结果

CPP中纳米姜黄素百分比增加,溶解度随之增加。30天后,5%CPP和ZOE的溶解度无显著差异(P = 1.000)。根据比色测试,3个月后,20%CPP的变色程度最高(8.45),Metapex的变色程度最小(4.06)。5%CPP和10%CPP的变色情况与ZOE的颜色变化相似(P>0.05)。

结论

本研究结果表明,牙髓糊剂的溶解度随姜黄素浓度的增加而增加。因此,可根据患者年龄、乳牙预期脱落时间和牙髓糊剂的溶解情况,使用不同纳米姜黄素浓度的牙髓糊剂。关于3个月后的变色情况,Metapex是最佳材料,变色率最高的是20%CPP,5%CPP和10%CPP与ZOE之间无差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa0a/10300143/7456023a2917/JDS-24-226-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验