Ikeda A, Hirata A, Miyazaki K, Fujita Y
Hinyokika Kiyo. 1986 Apr;32(4):619-23.
Buprenorphine, a new analgesic, was administered at a dose of 0.2 mg by intramuscular injection to 21 patients with acute ureteral colic. The patients consisted of 14 males and 7 females with a mean age of 42. In all cases, the diagnosis was confirmed based on intravenous urography performed after the treatment. In 19 of the 21 patients, colicky pain was reduced at least within one hour after the administration of buprenorphine. No significant changes in the pulse or blood pressure were observed. In 6 patients, mild dizziness or nausea was observed, and none of the patients required withdrawal of the treatment. Clinical use of buprenorphine was considered to the effective and safe in patients with ureteral colic.
新型镇痛药丁丙诺啡以0.2毫克的剂量通过肌肉注射给予21例急性输尿管绞痛患者。患者包括14名男性和7名女性，平均年龄为42岁。在所有病例中，诊断均在治疗后通过静脉肾盂造影得以证实。21例患者中有19例在注射丁丙诺啡后至少1小时内绞痛减轻。未观察到脉搏或血压有显著变化。6例患者出现轻度头晕或恶心，无一例患者需要停止治疗。丁丙诺啡在输尿管绞痛患者中的临床应用被认为是有效且安全的。
