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皮肤结节病:未确诊皮肤病变时需考虑的鉴别诊断。

Cutaneous Sarcoidosis: A Differential Diagnosis to Consider in Undiagnosed Skin Lesions.

作者信息

Islam Sumona, Hossain Md Sabbir, Murshed Khaled M, Rahaman Mohammad Ferdous Ur, Azad Md Abul Kalam

机构信息

Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.

Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.

出版信息

Cureus. 2023 Jun 1;15(6):e39852. doi: 10.7759/cureus.39852. eCollection 2023 Jun.

Abstract

The presentation of sarcoidosis varies depending on the organs involved. Cutaneous sarcoidosis usually presents with other organ involvement, but isolated presentation is possible. However, diagnosing isolated cutaneous sarcoidosis can be challenging in resource-poor countries, particularly where sarcoidosis is relatively uncommon, since cutaneous sarcoidosis usually does not cause troublesome symptoms. We present a case of cutaneous sarcoidosis in an elderly female who had been suffering from skin lesions for nine years. The diagnosis was made after the appearance of lung involvement, which raised the suspicion of sarcoidosis and prompted a skin biopsy. The patient was then treated with systemic steroids and methotrexate, and her lesions improved shortly thereafter. This case highlights the importance of considering sarcoidosis as a possible cause of undiagnosed, refractory cutaneous lesions.

摘要

结节病的表现因受累器官而异。皮肤结节病通常伴有其他器官受累,但也可能单独出现。然而,在资源匮乏的国家,诊断孤立性皮肤结节病可能具有挑战性,尤其是在结节病相对不常见的地区,因为皮肤结节病通常不会引起令人烦恼的症状。我们报告一例老年女性皮肤结节病病例,该患者皮肤病变已持续九年。在出现肺部受累后作出诊断,这引发了对结节病的怀疑并促使进行皮肤活检。随后患者接受了全身类固醇和甲氨蝶呤治疗,此后不久其病变有所改善。该病例强调了将结节病视为未确诊的难治性皮肤病变可能病因的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c3/10314976/61acf75caacf/cureus-0015-00000039852-i01.jpg

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