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评估某些中间冲洗剂在预防根管系统内次氯酸钠和氯己定形成沉淀物方面的效果:一项体外研究。

Evaluating the Efficacy of Certain Intermediate Irrigants in Preventing Precipitate Formed Due to Sodium Hypochlorite and Chlorhexidine Within the Root Canal System: An In Vitro Study.

作者信息

Patil Rucha, Singh Sarita V, Mandlik Jyoti S, Jadhav Aniket, Handa Aishwarya, Jadhav Abhijeet

机构信息

Department of Conservative Dentistry and Endodontics, Bharati Vidyapeeth Dental College and Hospital, Pune, IND.

出版信息

Cureus. 2023 Jun 2;15(6):e39871. doi: 10.7759/cureus.39871. eCollection 2023 Jun.

Abstract

AIM

Root canal irrigation using a mixture of sodium hypochlorite (NaOCL) and chlorhexidine gluconate (CHX) might cause a precipitate to develop. This study aims to check the efficacy of sodium thiosulfate and normal saline as irrigating solutions.

MATERIALS AND METHODS

Roots of 45 teeth were biomechanically prepared, and the teeth were then tested. A size 15k file was introduced to the point where the apical foramen could be visible in order to provide an accurate reading of the working length. As a precaution against irrigating solutions leaking out, the specimens' tips were sealed with modeling wax before being instrumented. Each group's root canals were instrumented with #F4 hand Protaper (Dentsply Sirona, USA) as recommended by the manufacturer. Between instrumentation, The canals were lubricated with ethylenediamine tetraacetic acid (EDTA) and irrigated with 2.5% sodium hypochlorite (RC Help, Prime Dental, Mumbai, India). Fifteen samples were randomly assigned to one of three experimental categories based on the middle watering arrangement used: Group 1 (control), Group 2 (saline irrigant), and Group 3 (3.86% sodium thiosulfate). The jewel plate was submerged in water to cool it down, while two longitudinal scores were made on the root's buccal and lingual surfaces. We used a stereomicroscope to examine the exposed surfaces of the root trench in the coronal, middle, and apical thirds for the orange-earthy colored material (Stereozoom Nikon magnifying lens under 20X amplification), and we used the Mann-Whitney U test and the Kruskal Wallis test during our thorough analysis.

RESULTS

The precipitation generated in the coronal, middle, and apical thirds had significantly different thicknesses. While precipitation did occur in all three regions, it was at a much lower rate in the apical third compared to the coronal and middle regions. In Group 1, the control group, the precipitate was thicker than in Groups 2 (saline irrigant) and 3 (3.86% sodium thiosulfate).

CONCLUSION

Sodium thiosulfate, which is a biocompatible solution, can be used as an intermediate irrigant as it shows less precipitate as compared to saline.

摘要

目的

使用次氯酸钠(NaOCL)和葡萄糖酸氯己定(CHX)的混合物进行根管冲洗可能会导致沉淀物形成。本研究旨在检验硫代硫酸钠和生理盐水作为冲洗液的效果。

材料与方法

对45颗牙齿的牙根进行生物力学预备,然后对牙齿进行测试。引入一根15号K锉至能看到根尖孔的位置,以便准确读取工作长度。为防止冲洗液漏出,在器械操作前用模型蜡密封标本的尖端。每组的根管按照制造商的建议用#F4手动Protaper(美国登士柏西诺德公司)进行器械预备。在器械预备之间,用乙二胺四乙酸(EDTA)润滑根管,并用2.5%的次氯酸钠(RC Help,印度孟买Prime Dental公司)冲洗。根据中间冲洗安排,将15个样本随机分配到三个实验类别之一:第1组(对照组)、第2组(生理盐水冲洗剂)和第3组(3.86%硫代硫酸钠)。将宝石盘浸入水中冷却,同时在牙根的颊侧和舌侧表面制作两条纵向划痕。我们使用体视显微镜检查根管冠部、中部和根尖三分之一处暴露表面的橙土色物质(尼康20倍放大体视变焦镜头),并在全面分析过程中使用曼-惠特尼U检验和克鲁斯卡尔-沃利斯检验。

结果

在冠部、中部和根尖三分之一处产生的沉淀物厚度有显著差异。虽然在所有三个区域都确实发生了沉淀,但与冠部和中部区域相比,根尖三分之一处的沉淀速率要低得多。在第1组对照组中,沉淀物比第2组(生理盐水冲洗剂)和第3组(3.86%硫代硫酸钠)更厚。

结论

硫代硫酸钠是一种生物相容性溶液,与生理盐水相比沉淀较少,可作为中间冲洗剂使用。

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