Dehkordi Fatemeh Jafarian, Farani Abbas Ramezani, Gharraee Banafsheh, Shati Mohsen, Ashouri Ahmad
Department of Clinical and Applied Psychology, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, Iran.
Mental Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Sciences (IUMS), Tehran, Iran.
J Educ Health Promot. 2023 May 31;12:181. doi: 10.4103/jehp.jehp_324_22. eCollection 2023.
Cognitive behavioral therapy (CBT) including exposure and response prevention (ERP) is the most effective and first-line treatment for obsessive-compulsive disorder (OCD). However, a significant number of people leave it or do not respond to it effectively. The present study aimed to examine the efficacy of personalized-computerized inhibitory training (P-CIT) program combined with ERP on treatment outcomes in patients with contamination OCD.
The present research method was based on an experimental design with pre-test, post-test, and the two intervention and control groups. Thirty patients with contamination OCD were randomly assigned to the two groups of intervention and control based on the inclusion and exclusion criteria. The measures used in this study were Yale-Brown Scale, Stroop task, World Health Organization's Quality of Life Questionnaire, Structured Clinical Interview for DSM-5, and Depression Anxiety and Stress Scales -21.
The results showed a significant reduction in severity of symptoms (F = 0.75, < 001) and severity of anxiety (F = 0.75, < 001) for the intervention group. Furthermore, task control (F = 12.44, < 001), mental health (F = 28.32, < 001), physical health (F = 2.48, < 001), and overall quality of life (F = 0.19, = 001) improved in the intervention group after the intervention.
When P-CIT is exerted along with ERP, it may enhance inhibition of compulsions and increase the efficacy of ERP through improved task control, thereby resulting in reduced symptom severity and improved treatment outcomes in patients with contamination OCD.
包括暴露与反应阻止法（ERP）在内的认知行为疗法（CBT）是强迫症（OCD）最有效且一线的治疗方法。然而，相当一部分人放弃该疗法或对其反应不佳。本研究旨在探讨个性化计算机抑制训练（P-CIT）计划联合ERP对污染型强迫症患者治疗效果的影响。
本研究方法基于一项包含预测试、后测试以及两个干预组和对照组的实验设计。根据纳入和排除标准，将30例污染型强迫症患者随机分为干预组和对照组。本研究使用的测量工具包括耶鲁-布朗量表、斯特鲁普任务、世界卫生组织生活质量问卷、《精神疾病诊断与统计手册》第5版结构化临床访谈以及抑郁焦虑压力量表-21。
结果显示，干预组的症状严重程度（F = 0.75，P < 0.001）和焦虑严重程度（F = 0.75，P < 0.001）显著降低。此外，干预后干预组的任务控制能力（F = 12.44，P < 0.001）、心理健康状况（F = 28.32，P < 0.001）、身体健康状况（F = 2.48，P < 0.001）以及总体生活质量（F = 0.19，P = 0.001）均有所改善。
当P-CIT与ERP联合使用时，它可能通过改善任务控制来增强对强迫行为的抑制，并提高ERP的疗效，从而降低污染型强迫症患者的症状严重程度并改善治疗效果。
