Institute for Biomedical Mechatronics, Johannes Kepler University, 4040 Linz, Austria.
Department of Cardiology, Kepler University Hospital, 4020 Linz, Austria.
Sensors (Basel). 2023 Jun 13;23(12):5552. doi: 10.3390/s23125552.
Models of the human body representing digital twins of patients have attracted increasing interest in clinical research for the delivery of personalized diagnoses and treatments to patients. For example, noninvasive cardiac imaging models are used to localize the origin of cardiac arrhythmias and myocardial infarctions. The precise knowledge of a few hundred electrocardiogram (ECG) electrode positions is essential for their diagnostic value. Smaller positional errors are obtained when extracting the sensor positions, along with the anatomical information, for example, from X-ray Computed Tomography (CT) slices. Alternatively, the amount of ionizing radiation the patient is exposed to can be reduced by manually pointing a magnetic digitizer probe one by one to each sensor. An experienced user requires at least 15 min. to perform a precise measurement. Therefore, a 3D depth-sensing camera system was developed that can be operated under adverse lighting conditions and limited space, as encountered in clinical settings. The camera was used to record the positions of 67 electrodes attached to a patient's chest. These deviate, on average, by 2.0 mm ±1.5 mm from manually placed markers on the individual 3D views. This demonstrates that the system provides reasonable positional precision even when operated within clinical environments.
代表患者数字双胞胎的人体模型在为患者提供个性化诊断和治疗方面的临床研究中引起了越来越多的关注。例如，无创心脏成像模型用于定位心脏心律失常和心肌梗死的起源。精确了解几百个心电图 (ECG) 电极位置对于其诊断价值至关重要。通过从 X 射线计算机断层扫描 (CT) 切片中提取传感器位置以及解剖信息，可以获得更小的位置误差。或者，可以通过手动将磁数字化仪探头一个一个地指向每个传感器，来减少患者受到的电离辐射量。有经验的用户至少需要 15 分钟才能进行精确测量。因此，开发了一种 3D 深度感应摄像头系统，该系统可以在临床环境中遇到的不利照明条件和有限空间下运行。该摄像头用于记录贴在患者胸部的 67 个电极的位置。这些位置与在各个 3D 视图上手动放置的标记平均偏差 2.0 毫米±1.5 毫米。这表明即使在临床环境中操作，该系统也能提供合理的位置精度。
