Zhang Baohu, Zhou Jie, Xie Guancong, Zhang Li, Zhang Yang, Xu Kangli, Feng Tianyuan, Yang Shucai
Department of Clinical Laboratory, Pingshan General Hospital, Southern Medical University (Pingshan District People's Hospital of Shenzhen), Shenzhen, Guangdong, People's Republic of China.
Department of Cardiovascular Medicine, Pingshan General Hospital, Southern Medical University (Pingshan District People's Hospital of Shenzhen), Shenzhen, Guangdong, People's Republic of China.
Infect Drug Resist. 2023 Jul 3;16:4285-4288. doi: 10.2147/IDR.S416387. eCollection 2023.
has been previously reported in isolated cases of bacterial endocarditis and liver abscesses. Its presence in urine is generally considered a contaminant. A 66-year-old male patient was admitted to the hospital due to recurrent chest tightness and four-year history of exertional dyspnea. On the second day of admission, the patient presented with urgent and frequent urination, as well as dysuria. Both initial and subsequent urine cultures showed infection, with polymorphonuclear leukocyte phagocytosis observed in the second sample. MALDI-TOF results confirmed the isolated strain as . Drug susceptibility testing revealed multidrug resistance to penicillin, ceftriaxone, cefepime, levofloxacin, ofloxacin, and tetracycline, but sensitivity to quinupristin/dalfopristin, vancomycin, and linezolid. The clinician then prescribed vancomycin for anti-infective treatment, which proved effective. Keywords: , UTI, MDR, phagocytosis.
先前已在孤立的细菌性心内膜炎和肝脓肿病例中报道过。其在尿液中的存在通常被认为是一种污染物。一名66岁男性患者因反复胸闷和四年劳力性呼吸困难病史入院。入院第二天，患者出现尿急、尿频以及排尿困难。初始和后续尿液培养均显示有感染，在第二个样本中观察到多形核白细胞吞噬现象。基质辅助激光解吸电离飞行时间质谱（MALDI-TOF）结果证实分离出的菌株为 。药敏试验显示对青霉素、头孢曲松、头孢吡肟、左氧氟沙星、氧氟沙星和四环素具有多重耐药性，但对奎奴普丁/达福普汀、万古霉素和利奈唑胺敏感。然后临床医生开了万古霉素进行抗感染治疗，结果证明有效。关键词： ，尿路感染，多重耐药，吞噬作用 。 （注：原文中部分关键信息缺失，用“ ”表示）
