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非洲肌肉减少症的患病率:系统评价。

Prevalence of Sarcopenia in Africa: A Systematic Review.

机构信息

Department of Bio & Medical Big Data, Gyeongsang National University Hospital, Jinju, South Korea.

Department of Biomedical Research Institute, Gyeongsang National University Hospital, Jinju, South Korea.

出版信息

Clin Interv Aging. 2023 Jul 4;18:1021-1035. doi: 10.2147/CIA.S407917. eCollection 2023.

Abstract

OBJECTIVE

The world population gradually getting older, age-related sarcopenia is becoming more frequent. Known to be highly prevalent in high income countries, relative data in Africa are still scarce. This review aims to estimate the prevalence of sarcopenia in Africa and its characteristics.

STUDY DESIGN AND SETTING

A literature search in PubMed, Web of Science, Google Scholar, and Scopus was conducted in October 2022. All studies reporting the prevalence of sarcopenia in Africa within 15 years were included, and we did an assessment of bias with Hoy et al's risk bias assessment tool. The estimated prevalence of sarcopenia was the outcome and we performed secondary analyses by age, gender, and diagnostic criteria. The random effect model was used for the prevalence estimation. The prevalence of sarcopenia and 95% confidence interval (95% CI) were calculated using the inverse-variance method.

RESULTS

A total of 17 studies met our eligibility criteria, for a study population of 12,690 participants with 44.3% males and 55.7% females. The overall prevalence of sarcopenia was 25% (95% CI: 19-30%). The prevalence of sarcopenia among 50 years old and older was 23% (95% CI: 17-29%). We had a higher prevalence of sarcopenia among males (30%, %95 IC: 20-39%) than females (29%, %95 IC: 21-36%). The prevalence of sarcopenia was different depending on the diagnosis criteria used.

CONCLUSION

The prevalence of sarcopenia in Africa was relatively high. However, the fact that the majority of included studies were hospital-based studies shows the necessity of further community-based studies in order to have a more accurate representation of the situation in the general population.

摘要

目的

随着世界人口逐渐老龄化,与年龄相关的肌肉减少症变得更加普遍。已知这种疾病在高收入国家的发病率很高,而非洲相关数据仍然很少。本综述旨在评估非洲肌肉减少症的患病率及其特征。

研究设计和设置

2022 年 10 月,我们在 PubMed、Web of Science、Google Scholar 和 Scopus 上进行了文献检索。纳入了所有在 15 年内报告过非洲肌肉减少症患病率的研究,并使用 Hoy 等人的风险偏倚评估工具评估了偏倚。肌肉减少症的患病率是研究结果,我们进行了年龄、性别和诊断标准的二次分析。使用随机效应模型进行患病率估计。使用逆方差法计算肌肉减少症的患病率和 95%置信区间(95%CI)。

结果

共有 17 项研究符合纳入标准,研究人群为 12690 名参与者,其中 44.3%为男性,55.7%为女性。总体肌肉减少症患病率为 25%(95%CI:19-30%)。50 岁及以上人群的肌肉减少症患病率为 23%(95%CI:17-29%)。男性(30%,95%CI:20-39%)的肌肉减少症患病率高于女性(29%,95%CI:21-36%)。不同的诊断标准会导致肌肉减少症的患病率不同。

结论

非洲肌肉减少症的患病率相对较高。然而,由于大多数纳入的研究都是基于医院的研究,因此需要进一步开展基于社区的研究,以便更准确地反映普通人群的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efc5/10329476/327f067b102d/CIA-18-1021-g0001.jpg

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