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基于眼球运动的神经康复系统对慢性脑卒中损伤水平的神经功能相关性:一项初步研究。

Neurofunctional correlates of a neurorehabilitation system based on eye movements in chronic stroke impairment levels: A pilot study.

机构信息

Departamento de Ciencias Médicas Básicas, Universidad de la Laguna, Tenerife, Spain.

Instituto de Tecnologías Biomédicas, Universidad de la Laguna, Tenerife, Spain.

出版信息

Brain Behav. 2023 Aug;13(8):e3049. doi: 10.1002/brb3.3049. Epub 2023 Jul 11.

DOI:10.1002/brb3.3049
PMID:37434341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10454340/
Abstract

INTRODUCTION

Rehabilitation after a stroke is widely considered fundamental to improve secondary functional impairments. Accessible methods based on motor learning, motor transfer and virtual environments are necessary to help to improve stroke patients' quality of life.

OBJECTIVES

Continuing the line of our previous studies, this work investigated the effect of our new and innovative game-based virtual reality training using the control of virtual objects with gaze in three chronic stroke survivors.

METHODS

All participants performed an eye-controlled virtual training task for 4 weeks. Pre- and post-training evaluation were carried out with the Fugl-Meyer Assessment for upper extremity scale as well as performing a tracking task inside an MRI scanner with a MRI-compatible eye-tracker or a joystick.

RESULTS

Neural results for each participant show the increase of activity in the motor cortex, basal ganglia and cerebellum for both effectors (hand or eye).

CONCLUSION

These promising results have a potential application as a new game-based neurorehabilitation approach to enhance the motor activity of stroke patients.

摘要

简介

脑卒中后的康复被广泛认为是改善继发性功能障碍的基础。基于运动学习、运动转移和虚拟环境的可及方法对于提高脑卒中患者的生活质量是必要的。

目的

延续我们之前研究的思路,本研究调查了我们使用注视控制虚拟对象的新型创新基于游戏的虚拟现实训练对 3 名慢性脑卒中幸存者的影响。

方法

所有参与者均进行了为期 4 周的眼控虚拟训练任务。在训练前后,使用 Fugl-Meyer 上肢评估量表以及使用与 MRI 兼容的眼动追踪器或操纵杆在 MRI 扫描仪内进行跟踪任务进行评估。

结果

每位参与者的神经结果都显示出,对于两种效应器(手或眼),运动皮层、基底节和小脑的活动都增加了。

结论

这些有前景的结果可作为一种新的基于游戏的神经康复方法应用,以增强脑卒中患者的运动活动能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/b1bdc3cf2315/BRB3-13-e3049-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/a2158f252a63/BRB3-13-e3049-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/08420c5535f9/BRB3-13-e3049-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/c52ac999c1dd/BRB3-13-e3049-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/3892710d6941/BRB3-13-e3049-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/b1bdc3cf2315/BRB3-13-e3049-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/a2158f252a63/BRB3-13-e3049-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/08420c5535f9/BRB3-13-e3049-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/c52ac999c1dd/BRB3-13-e3049-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/3892710d6941/BRB3-13-e3049-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/030c/10454340/b1bdc3cf2315/BRB3-13-e3049-g002.jpg

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J Cardiovasc Dev Dis. 2023 Jan 28;10(2):50. doi: 10.3390/jcdd10020050.
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The neural correlates of intermanual transfer.双手间转移的神经关联。
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Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
1990—2019年全球、区域和国家的卒中负担及其风险因素:全球疾病负担研究2019的系统分析
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The Roles of the Cortical Motor Areas in Sequential Movements.皮质运动区在连续运动中的作用。
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Posterior Circulation Endovascular Thrombectomy for Large-Vessel Occlusion: Predictors of Favorable Clinical Outcome and Analysis of First-Pass Effect.后循环血管内血栓切除术治疗大血管闭塞:良好临床结局的预测因素及初次通过效果分析。
AJNR Am J Neuroradiol. 2021 May;42(5):896-903. doi: 10.3174/ajnr.A7023. Epub 2021 Mar 4.
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A novel fully immersive virtual reality environment for upper extremity rehabilitation in patients with stroke.一种新型沉浸式虚拟现实环境,用于脑卒中患者上肢康复。
Ann N Y Acad Sci. 2021 Jun;1493(1):75-89. doi: 10.1111/nyas.14554. Epub 2021 Jan 14.
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Enhancing Brain Plasticity to Promote Stroke Recovery.增强脑可塑性以促进中风恢复。
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