Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
United Imaging Intelligence, Cambridge, Massachusetts, USA.
J Magn Reson Imaging. 2024 Apr;59(4):1231-1241. doi: 10.1002/jmri.28899. Epub 2023 Jul 12.
Conventional segmented, retrospectively gated cine (Conv-cine) is challenged in patients with breath-hold difficulties. Compressed sensing (CS) has shown values in cine imaging but generally requires long reconstruction time. Recent artificial intelligence (AI) has demonstrated potential in fast cine imaging.
To compare CS-cine and AI-cine with Conv-cine in quantitative biventricular functions, image quality, and reconstruction time.
Prospective human studies.
70 patients (age, 39 ± 15 years, 54.3% male).
FIELD STRENGTH/SEQUENCE: 3T; balanced steady state free precession gradient echo sequences.
Biventricular functional parameters of CS-, AI-, and Conv-cine were measured by two radiologists independently and compared. The scan and reconstruction time were recorded. Subjective scores of image quality were compared by three radiologists.
Paired t-test and two related-samples Wilcoxon sign test were used to compare biventricular functional parameters between CS-, AI-, and Conv-cine. Intraclass correlation coefficient (ICC), Bland-Altman analysis, and Kendall's W method were applied to evaluate agreement of biventricular functional parameters and image quality of these three sequences. A P-value <0.05 was considered statistically significant, and standardized mean difference (SMD) < 0. 100 was considered no significant difference.
Compared to Conv-cine, no statistically significant differences were identified in CS- and AI-cine function results (all P > 0.05), except for very small differences in left ventricle end-diastole volumes of 2.5 mL (SMD = 0.082) and 4.1 mL (SMD = 0.096), respectively. Bland-Altman scatter plots revealed that biventricular function results were mostly distributed within the 95% confidence interval. All parameters had acceptable to excellent interobserver agreements (ICC: 0.748-0.989). Compared with Conv-cine (84 ± 13 sec), both CS (14 ± 2 sec) and AI (15 ± 2 sec) techniques reduced scan time. Compared with CS-cine (304 ± 17 sec), AI-cine (24 ± 4 sec) reduced reconstruction time. CS-cine demonstrated significantly lower quality scores than Conv-cine, while AI-cine demonstrated similar scores (P = 0.634).
CS- and AI-cine can achieve whole-heart cardiac cine imaging in a single breath-hold. Both CS- and AI-cine have the potential to supplement the gold standard Conv-cine in studying biventricular functions and benefit patients having difficulties with breath-holds.
1 TECHNICAL EFFICACY STAGE: 1.
常规的分段回顾性门控电影（Conv-cine）在有屏气困难的患者中受到挑战。压缩感知（CS）在电影成像中显示出了价值，但通常需要较长的重建时间。最近的人工智能（AI）在快速电影成像方面显示出了潜力。
比较 CS 电影和 AI 电影与 Conv-cine 在定量双心室功能、图像质量和重建时间方面的差异。
前瞻性人体研究。
70 名患者（年龄 39±15 岁，54.3%为男性）。
磁场强度/序列：3T；平衡稳态自由进动梯度回波序列。
由两位放射科医生独立测量 CS、AI 和 Conv-cine 的双心室功能参数，并进行比较。记录扫描和重建时间。三位放射科医生比较图像质量的主观评分。
采用配对 t 检验和两相关样本 Wilcoxon 符号秩检验比较 CS、AI 和 Conv-cine 之间的双心室功能参数。采用组内相关系数（ICC）、Bland-Altman 分析和 Kendall's W 方法评估这三种序列的双心室功能参数和图像质量的一致性。P 值<0.05 被认为具有统计学意义，标准化均数差（SMD）<0.100 被认为无显著差异。
与 Conv-cine 相比，CS 和 AI 电影的功能结果没有统计学差异（均 P>0.05），除左心室舒张末期容积分别有非常小的差异（SMD=0.082 和 0.096）外。Bland-Altman 散点图显示，双心室功能结果主要分布在 95%置信区间内。所有参数的观察者间一致性均为可接受至极好（ICC：0.748-0.989）。与 Conv-cine（84±13 秒）相比，CS（14±2 秒）和 AI（15±2 秒）技术均缩短了扫描时间。与 CS 电影（304±17 秒）相比，AI 电影（24±4 秒）缩短了重建时间。CS 电影的质量评分明显低于 Conv-cine，而 AI 电影的评分相似（P=0.634）。
CS 和 AI 电影可以在单次屏气中实现全心电影成像。CS 和 AI 电影都有可能补充常规的 Conv-cine 作为研究双心室功能的金标准，并使有屏气困难的患者受益。
1 技术功效等级：1。
