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新冠病毒感染后症状较为常见,普通人群中的青年群体也不例外。

Post COVID-19 symptoms are common, also among young adults in the general population.

机构信息

Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

Center for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden.

出版信息

Sci Rep. 2023 Jul 12;13(1):11300. doi: 10.1038/s41598-023-38315-2.

Abstract

Post coronavirus disease-19 (post COVID-19) is mainly studied in clinical populations and less is known about post COVID-19 in a young general population. The aim of the study is to investigate the prevalence and symptoms of post COVID-19 and its potential risk factors in young adults. Participants from the Swedish population-based birth cohort BAMSE were included (n = 2022, mean age 26.5 years). Post COVID-19 was assessed through a questionnaire and defined as symptoms after confirmed COVID-19 (registry-based or self-reported positive test) lasting for ≥ 2 months. In total, 681 participants had had confirmed COVID-19. Among them, 112 (16.5%) fulfilled the definition of post COVID-19 (17.8% in females, 14.5% in males, p = 0.26). The most common post COVID-19 symptoms were altered smell and taste (68.8%), dyspnea (33.7%) and fatigue (30.4%). Overall, no major risk factors for post COVID-19 were identified except for being bedbound during COVID-19. However, asthma and rhinitis were associated with the post COVID-19 symptom dyspnea, migraine with altered smell and taste, and lower self-rated health with fatigue. In conclusion, post COVID-19 symptoms are common, also among young adults in the general population. Although not life-threatening, it could have a considerable impact on public health due to the high prevalence and long-term symptoms.

摘要

新冠病毒病(COVID-19)后(post COVID-19)主要在临床人群中进行研究,而在年轻的普通人群中对 COVID-19 后(post COVID-19)的了解较少。本研究旨在调查年轻成年人中 COVID-19 后(post COVID-19)的患病率、症状及其潜在危险因素。参与者来自瑞典基于人群的出生队列 BAMSE(n=2022,平均年龄 26.5 岁)。通过问卷评估 COVID-19 后(post COVID-19),并将其定义为确诊 COVID-19(基于登记或自我报告的阳性检测)后持续≥2 个月的症状。共有 681 名参与者确诊 COVID-19。其中,112 名(16.5%)符合 COVID-19 后(post COVID-19)的定义(女性 17.8%,男性 14.5%,p=0.26)。最常见的 COVID-19 后(post COVID-19)症状是嗅觉和味觉改变(68.8%)、呼吸困难(33.7%)和疲劳(30.4%)。总体而言,除 COVID-19 期间卧床不起外,未发现 COVID-19 后(post COVID-19)的主要危险因素。然而,哮喘和鼻炎与 COVID-19 后(post COVID-19)症状呼吸困难有关,偏头痛与嗅觉和味觉改变有关,自我评估健康状况较差与疲劳有关。总之,COVID-19 后(post COVID-19)症状很常见,在普通人群中的年轻成年人中也是如此。尽管 COVID-19 后(post COVID-19)不危及生命,但由于高患病率和长期症状,它可能对公共卫生产生重大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b1a/10338459/7bb7ce6577d2/41598_2023_38315_Fig1_HTML.jpg

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