Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Center for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden.
Sci Rep. 2023 Jul 12;13(1):11300. doi: 10.1038/s41598-023-38315-2.
Post coronavirus disease-19 (post COVID-19) is mainly studied in clinical populations and less is known about post COVID-19 in a young general population. The aim of the study is to investigate the prevalence and symptoms of post COVID-19 and its potential risk factors in young adults. Participants from the Swedish population-based birth cohort BAMSE were included (n = 2022, mean age 26.5 years). Post COVID-19 was assessed through a questionnaire and defined as symptoms after confirmed COVID-19 (registry-based or self-reported positive test) lasting for ≥ 2 months. In total, 681 participants had had confirmed COVID-19. Among them, 112 (16.5%) fulfilled the definition of post COVID-19 (17.8% in females, 14.5% in males, p = 0.26). The most common post COVID-19 symptoms were altered smell and taste (68.8%), dyspnea (33.7%) and fatigue (30.4%). Overall, no major risk factors for post COVID-19 were identified except for being bedbound during COVID-19. However, asthma and rhinitis were associated with the post COVID-19 symptom dyspnea, migraine with altered smell and taste, and lower self-rated health with fatigue. In conclusion, post COVID-19 symptoms are common, also among young adults in the general population. Although not life-threatening, it could have a considerable impact on public health due to the high prevalence and long-term symptoms.
新冠病毒病(COVID-19)后(post COVID-19)主要在临床人群中进行研究,而在年轻的普通人群中对 COVID-19 后(post COVID-19)的了解较少。本研究旨在调查年轻成年人中 COVID-19 后(post COVID-19)的患病率、症状及其潜在危险因素。参与者来自瑞典基于人群的出生队列 BAMSE(n=2022,平均年龄 26.5 岁)。通过问卷评估 COVID-19 后(post COVID-19),并将其定义为确诊 COVID-19(基于登记或自我报告的阳性检测)后持续≥2 个月的症状。共有 681 名参与者确诊 COVID-19。其中,112 名(16.5%)符合 COVID-19 后(post COVID-19)的定义(女性 17.8%,男性 14.5%,p=0.26)。最常见的 COVID-19 后(post COVID-19)症状是嗅觉和味觉改变(68.8%)、呼吸困难(33.7%)和疲劳(30.4%)。总体而言,除 COVID-19 期间卧床不起外,未发现 COVID-19 后(post COVID-19)的主要危险因素。然而,哮喘和鼻炎与 COVID-19 后(post COVID-19)症状呼吸困难有关,偏头痛与嗅觉和味觉改变有关,自我评估健康状况较差与疲劳有关。总之,COVID-19 后(post COVID-19)症状很常见,在普通人群中的年轻成年人中也是如此。尽管 COVID-19 后(post COVID-19)不危及生命,但由于高患病率和长期症状,它可能对公共卫生产生重大影响。