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腹腔镜与机器人腹部和盆腔手术:随机对照试验的系统评价。

Laparoscopic versus robotic abdominal and pelvic surgery: a systematic review of randomised controlled trials.

机构信息

Department of Medicine, Imperial College London, London, UK.

Department of Surgery, City of Hope Medical Center, Duarte, CA, 91010, USA.

出版信息

Surg Endosc. 2023 Sep;37(9):6672-6681. doi: 10.1007/s00464-023-10275-8. Epub 2023 Jul 13.

Abstract

BACKGROUND

The current evidence is inconclusive on whether robotic or laparoscopic surgery is the optimal platform for minimally invasive surgery. Existing comparisons techniques focus on short-term outcomes only, while potentially being confounded by a lack of standardisation in robotic procedures. There is a pertinent need for an up-to-date comparison between minimally invasive surgical techniques. We aimed to systematically review randomised controlled trials comparing robotic and laparoscopic techniques in major surgery.

METHODS

Embase, Medline and Cochrane Library were searched from their inception to 13th September 2022. Included studies were randomised controlled trials comparing robotic and laparoscopic techniques in abdominal and pelvic surgery. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Short-term, health-related quality of life, and long-term, outcomes were analysed.

RESULTS

Forty-five studies, across thirteen procedures, involving 7364 patients were included. All of the studies reported non-significant differences in mortality between robotic and laparoscopic surgery. In majority of studies, there was no significant difference in complication rate (n = 31/35, 85.6%), length of postoperative stay (n = 27/32, 84.4%), and conversion rate (n = 15/18, 83.3%). Laparoscopic surgery was associated with shorter operative time (n = 16/31, 51.6%) and lower total cost (n = 11/13, 84.6%). Twenty three studies reported on quality of life outcomes; majority (n = 14/23, 60.9%) found no significant differences.

CONCLUSION

There were no significant differences between robotic surgery and laparoscopic surgery with regards to mortality and morbidity outcomes in the majority of studies. Robotic surgery was frequently associated with longer operative times and higher overall cost. Selected studies found potential benefits in post-operative recovery time, and patient-reported outcomes; however, these were not consistent across procedures and trials, with most studies being underpowered to detect differences in secondary outcomes. Future research should focus on assessing quality of life, and long-term outcomes to further elucidate where the robotic platform could lead to patient benefits, as the technology evolves.

摘要

背景

目前,关于机器人手术和腹腔镜手术哪个是微创手术的最佳平台,尚无定论。现有的比较技术仅关注短期结果,而可能由于机器人手术缺乏标准化而受到混淆。因此,非常需要对微创手术技术进行最新的比较。我们旨在系统地综述比较腹部和盆腔手术中机器人和腹腔镜技术的随机对照试验。

方法

从建库到 2022 年 9 月 13 日,我们在 Embase、Medline 和 Cochrane Library 上进行了检索。纳入的研究是比较腹部和盆腔手术中机器人和腹腔镜技术的随机对照试验。该研究遵循系统评价和荟萃分析的首选报告项目 (PRISMA) 指南。分析了短期、健康相关生活质量和长期结局。

结果

共纳入 45 项研究,涉及 13 项手术,共 7364 例患者。所有研究报告机器人手术和腹腔镜手术的死亡率无显著差异。在大多数研究中,并发症发生率(n=31/35,85.6%)、术后住院时间(n=27/32,84.4%)和中转率(n=15/18,83.3%)无显著差异。腹腔镜手术的手术时间更短(n=16/31,51.6%),总费用更低(n=11/13,84.6%)。23 项研究报告了生活质量结果;大多数(n=14/23,60.9%)发现无显著差异。

结论

在大多数研究中,机器人手术和腹腔镜手术在死亡率和发病率方面没有显著差异。机器人手术通常与较长的手术时间和更高的总费用相关。一些选定的研究发现术后恢复时间和患者报告的结果有潜在的益处;然而,这些结果在不同的手术和试验中并不一致,大多数研究在检测次要结局方面的能力不足。未来的研究应侧重于评估生活质量和长期结局,以进一步阐明随着技术的发展,机器人平台如何为患者带来益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d186/10462573/4789beb76ee3/464_2023_10275_Fig1_HTML.jpg

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