da Silva Marielen Ribeiro Tavares, Costa Ana Paula, da Luz Amanda Almeida, Pelaio Caio Henrique, Cruz Felipe Baleche, Steil Giovanna Fischer, Giamberardino Heloisa Ihle Garcia, Prando Carolina
Faculdades Pequeno Príncipe, Curitiba 80230-020, PR, Brazil.
Instituto de Pesquisa Pelé Príncipe, Curitiba 80250-060, PR, Brazil.
J Clin Med. 2023 Jun 27;12(13):4325. doi: 10.3390/jcm12134325.
The coronavirus disease 2019 (COVID-19) pandemic began in Brazil on 26 February 2020. By 6 May 2023, 37.4 million cases had been confirmed, causing 701 thousand deaths in the country. We aimed to describe the epidemiological profile and clinical development of COVID-19 cases among the employees of a health institution, from acute infection to long COVID.
This was a longitudinal study using a retrospective and prospective approach via questionnaires referring to epidemiological investigation, which was the inclusion criteria, and about long-term symptoms.
A total of 809 employees were detected with SARS-CoV-2 infection via RT-PCR, 466 of them answered the epidemiological investigation, and 101 completed the Long COVID Symptom Questionnaire. The most commonly affected employees were women (88.6%) working in patient care (68.6%). Headache, myalgia, cough, odynophagia, and runny nose were the most frequent symptoms. Only three employees (0.6%) required hospitalization, while the other employees required outpatient management due to mild symptoms. We identified 19 (4.1%) cases of reinfection, and 42 (41.6%) employees reported long-term symptoms, such as myalgia, dyspnea, and headache.
Although most cases were mild with good outcomes, long COVID cases identified are noteworthy, as these symptoms may impact quality of life even months after SARS-CoV-2 infection.
2019年冠状病毒病（COVID-19）大流行于2020年2月26日在巴西开始。截至2023年5月6日，该国已确诊3740万例病例，导致70.1万人死亡。我们旨在描述一家卫生机构员工中COVID-19病例从急性感染到长期COVID的流行病学特征和临床发展情况。
这是一项纵向研究，采用回顾性和前瞻性方法，通过涉及流行病学调查（这是纳入标准）和长期症状的问卷进行。
通过逆转录聚合酶链反应（RT-PCR）共检测出809名员工感染了严重急性呼吸综合征冠状病毒2（SARS-CoV-2），其中466人回答了流行病学调查，101人完成了长期COVID症状问卷。受影响最常见的员工是从事患者护理工作的女性（88.6%）。头痛、肌痛、咳嗽、吞咽痛和流鼻涕是最常见的症状。只有三名员工（0.6%）需要住院治疗，其他员工因症状轻微需要门诊治疗。我们确定了19例（4.1%）再次感染病例，42名员工（41.6%）报告有长期症状，如肌痛、呼吸困难和头痛。
尽管大多数病例症状轻微，预后良好，但所发现的长期COVID病例值得关注，因为即使在SARS-CoV-2感染数月后，这些症状仍可能影响生活质量。
