National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang 550025, China.
Int J Mol Sci. 2023 Jun 27;24(13):10694. doi: 10.3390/ijms241310694.
1,2,3-Triazolium salts have demonstrated significant potential in the fields of medicine and agriculture, exhibiting exceptional antibacterial, antifungal, anticancer, and antileishmanial properties. Moreover, these salts can be utilized as additives or components to produce nano- and fiber-based materials with antibacterial properties. In this review, we summarize several synthetic strategies to obtain 1,2,3-triazolium salts and the structures of 1,2,3-triazolium derivatives with biological activities in the domains of pharmaceuticals, pesticides, and functional materials. Additionally, the structure-activity relationship (SAR) of 1,2,3-triazolium salts with different biological activities has been analyzed. Finally, this review presents the potential applications and prospects of 1,2,3-triazolium salts in the fields of agriculture, medicine, and industrial synthesis.
1,2,3-三唑盐在医学和农业领域显示出巨大的潜力，具有出色的抗菌、抗真菌、抗癌和抗利什曼原虫特性。此外，这些盐可用作添加剂或成分，以生产具有抗菌性能的纳米和纤维基材料。在这篇综述中，我们总结了几种获得 1,2,3-三唑盐的合成策略，以及具有药物、农药和功能材料领域生物活性的 1,2,3-三唑衍生物的结构。此外，还分析了具有不同生物活性的 1,2,3-三唑盐的结构-活性关系（SAR）。最后，本文综述了 1,2,3-三唑盐在农业、医学和工业合成领域的潜在应用和前景。
