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涉及高价碘盐的无过渡金属芳基化反应的最新进展。

Recent advances in transition-metal-free arylation reactions involving hypervalent iodine salts.

作者信息

Mamgain Ritu, Sakthivel Kokila, Singh Fateh V

机构信息

Department of Chemistry, SAS, Vellore Institute of Technology Chennai, Chennai-600 127, Tamil Nadu, India.

出版信息

Beilstein J Org Chem. 2024 Nov 13;20:2891-2920. doi: 10.3762/bjoc.20.243. eCollection 2024.

DOI:10.3762/bjoc.20.243
PMID:39559439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11572100/
Abstract

Diaryliodonium salts have become widely recognized as arylating agents in the last two decades. Both, symmetrical and unsymmetrical forms of these salts serve as effective electrophilic arylating reagents in various organic syntheses. The use of diaryliodoniums in C-C and carbon-heteroatom bond formations, particularly under metal-free conditions, has further enhanced the popularity of these reagents. In this review, we concentrate on various arylation reactions involving carbon and other heteroatoms, encompassing rearrangement reactions in the absence of any metal catalyst, and summarize advancements made in the last five years.

摘要

在过去二十年中，二芳基碘鎓盐已被广泛认可为芳基化试剂。这些盐的对称和不对称形式在各种有机合成中均作为有效的亲电芳基化试剂。二芳基碘鎓盐在碳-碳键和碳-杂原子键形成中的应用，特别是在无金属条件下，进一步提高了这些试剂的受欢迎程度。在本综述中，我们专注于涉及碳和其他杂原子的各种芳基化反应，包括在没有任何金属催化剂的情况下的重排反应，并总结过去五年所取得的进展。

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