Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Italian Study Group on Metabolic Bone Disorders (GISMO), 00132 Roma, Italy.
Nutrients. 2023 Jun 29;15(13):2969. doi: 10.3390/nu15132969.
Vitamin D plays a crucial role in calcium and phosphate metabolism, relating to bone health and preventing metabolic bone disorders such as rickets and osteomalacia. Vitamin D deficiency (serum 25-OH-D values <20 ng/mL or 50 nmol/L) is common also in Italian people; it is recommended to maintain levels above 30 ng/mL (75 nmol/L) in categories at risk. Supplementation and/or fortification with either ergocalciferol (vitamin D2) or cholecalciferol (vitamin D3) aimed to modify this condition have commonly been proposed. Studies about vitamin D intake are numerous in the literature but not adequately designed and are very often incomplete in Mediterranean Countries such as in the Italian population. On these bases, we performed a survey to validate a frequency food questionnaire (FFQ) specifically created to rapidly assess dietary vitamin D intake in Italian people. For this aim, the data of questionnaires were compared with results derived in the same population from a designed 14-day frequency food diary (FFD). Overall, a good correlation between FFQ and FFD was observed (r = 0.89, < 0.001), both demonstrating a remarkably low vitamin D intake, irrespective of age and gender. Our data confirm that the vitamin D intake is very low in Italy, which likely contributes to hypovitaminosis D.
维生素 D 在钙和磷代谢中起着至关重要的作用,与骨骼健康有关,并可预防代谢性骨病,如佝偻病和骨软化症。意大利人也普遍存在维生素 D 缺乏症(血清 25-羟维生素 D 值<20ng/ml 或 50nmol/L);建议高危人群的维生素 D 水平应保持在 30ng/ml(75nmol/L)以上。人们普遍建议通过补充或强化麦角钙化醇(维生素 D2)或胆钙化醇(维生素 D3)来改善这种情况。关于维生素 D 摄入量的研究在文献中很多,但设计不当,在像意大利这样的地中海国家往往不完整。基于这些原因,我们进行了一项调查,以验证一种专门用于快速评估意大利人膳食维生素 D 摄入量的频率食物问卷(FFQ)。为此,将问卷数据与同一人群从设计的 14 天频率食物日记(FFD)中得出的结果进行了比较。总体而言,FFQ 和 FFD 之间存在良好的相关性(r=0.89,<0.001),两者均表明维生素 D 摄入量极低,与年龄和性别无关。我们的数据证实,意大利的维生素 D 摄入量非常低,这可能导致维生素 D 缺乏症。