皮质类固醇诱导的急性梅毒性后极部扁平状脉络膜视网膜炎的调节
Corticosteroid-induced modulation of acute syphilitic posterior placoid chorioretinitis.
作者信息
Zamani Maryam, Garfinkel Richard A
机构信息
Department of Ophthalmology, George Washington University Hospital, (M.Z.), Washington, DC, USA.
出版信息
Am J Ophthalmol. 2003 Jun;135(6):891-4. doi: 10.1016/s0002-9394(02)02160-8.
PURPOSE
To report a case of corticosteroid-induced modulation of acute syphilitic posterior placoid chorioretinitis.
DESIGN
Interventional case report.
METHOD
A 38-year-old homosexual male who presented with a unilateral uveitis secondary to syphilis developed large placoid macular lesions after treatment with oral prednisone that resolved when the corticosteroids were discontinued.
RESULTS
A cause-and-effect relationship was demonstrated between oral prednisone and the appearance of acute syphilitic posterior placoid chorioretinitis.
CONCLUSIONS
The clinical appearance of posterior placoid chorioretinitis in syphilis may be modulated by the immune status of the patient.
目的
报告一例皮质类固醇诱导的急性梅毒性后极部扁平状脉络膜视网膜炎的病情变化。
设计
介入性病例报告。
方法
一名38岁的同性恋男性，因梅毒继发单侧葡萄膜炎，在口服泼尼松治疗后出现大片扁平状黄斑病变，停用皮质类固醇后病变消退。
结果
证实口服泼尼松与急性梅毒性后极部扁平状脉络膜视网膜炎的出现之间存在因果关系。
结论
梅毒患者后极部扁平状脉络膜视网膜炎的临床表现可能受患者免疫状态的影响。
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